Washington University

Keng-Ku Liu

Srikanth Singamaneni

Shantanu Chakrabartty

Evan David Kharasch

Jeremiah Morrissey

Yarub Alazzawi

Limei Tian

Srikanth Signamaneni

Mingquan Yuan

Abdennour Abbas

A sensor system includes a sensor module that is embedded in a target environment and a signal system. The sensor module includes an active sensor of a first type that detects a target element in the target environment and a reference sensor of the first type that prevents detection of target elements by the reference sensor. The active sensor and the reference sensor receive an ultrasonic signal and respectively generate a first response signal and a second response signal. The first response signal is at least partially as a function of the detected target element. The signal system includes an ultrasonic transducer that generates the ultrasonic signal and receives the first and second response signals, and a controller communicatively coupled to the ultrasonic transducer. The controller identifies the detected target element based at least partially on the first and second response signals.

Systems and methods for detecting embedded target elements using signal interference

Plasmonic nanotransducers, methods of preparing plasmonic nanotransducers, and methods for label-free detection of target molecules are disclosed. The plasmonic nanotransducers include hollow nanostructure cores and artificial antibodies. The plasmonic nanotransducers are exposed to a biological sample that can contain the specific target molecules. The plasmonic nanotransducers can be analyzed with surface enhanced Raman scattering techniques and/or localized surface plasmon resonance techniques to quantify the amount of the target molecule in the sample.

Plasmonic biosensors with built-in artificial antibodies

Growing community of inventors

Philadelphia, PA, United States of America

Keng-Ku Liu