Terumo Kabushiki Kaisha

Terumo Kabushiki Kaisha, Trading As Terumo Corporation

Ken Tatebe

Kousuke Kido

Manabu Yamazaki

Yuichi Mori

Yukio Seita

Kazuaki Takahara

Takeo Katakura

Jun Konishi

Mikio Koide

Kazuhiro Shimoda

Shoichi Nagaki

Kaori Oyamada

Ken-ichi Ohsaki

Katsuyuki Ooba

Takeshi Shimomura

Kenichi Shimura

Makoto Onishi

Toshiji Ichikawa

Juuro Aoyagi

Yoshimitsu Asada

Yoshitaka Ohmura

Takashi Ohwada

Tooru Takahashi

A test paper includes a porous membrane capable of separating an object that should be filtered out of a sample by filtration, the porous membrane carrying a reagent capable of reacting with a specified component of the sample to result in coloring. The porous membrane includes a first layer having a surface on which the sample is supplied and a second layer having a surface at which sample percolation and measuring are effected, the first layer composed of large pore portions, the surface of the first layer consisting of a smooth surface having open pore portions, the second layer composed of minute pore portions the surface of the second layer consisting of a surface having open pore portions. The porous membrane has a thickness of 50 to 200 &#x3bc;m and a porosity of 60 to 95%.

Test paper and porous membrane

A material wherein a polyamine compound is immobilized on its base surface and a blood filter using this material. The material is provided in the form of a porous membrane having the maximum pore diameter of 0.1-50 .mu.m. The polyamine compound is at least one compound selected from the group consisting of (a) a polyamine compound which has primary and secondary amines in its molecule and a hydrophobic part between these amines, (b) a polyamine compound represented by the following formula (I); ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 represent hydrogen, aliphatic and aromatic hydrocarbons, and halogen, and n is 5 or more, and (c) a polyamine compound represented by the following formula (II); ##STR2## wherein R represents NH.sub.2 or aminoalkyl radical having 1 to 4 carbon atoms and n is 5 or more. The blood filter comprises a housing which has an inlet and outlet, and the material arranged inside the housing.

Pathogenic substance removing material and a blood filter containing the

The present invention is directed to an oxygenator using a hydrophobic porous hollow fiber membrane possessing an inside diameter in the range of 150 to 300 microns, a wall thickness in the range of 10 to 150 microns, and a substantially circular cross section, which porous hollow fiber membrane possesses an average crimp amplitude in the range of 35 to 120% of the outside diameter, a maximum crimp amplitude/crimp half cycle period at maximum crimp amplitude ratio in the range of 0.01 to 0.1, and a crimp ratio in the range of 1.0 to 3.0%, and a method for the production thereof.

Oxygenator using porous hollow fiber membrane

A porous polypropylene hollow fiber membrane constructed and arranged for artificial lung use and an artificial lung. The membrane includes a solid phase in an inner surface region thereof formed with particles of polypropylene closely fused and joined to give rise to a continuous phase while partially exposed through the surface thereof, a solid phase in an interior and an outer surface region thereof formed with particles of polypropylene interconnected in the direction of axis of the fiber to give rise to a multiplicity of lumps of polyproplylene and an interstice between the phases having continuous pores interconnected in the form of a three-dimensional network.

Porous polypropylene membrane and method for production thereof

Cell-penetrable medical material made of denatured collagen which is prepared by heating, in the presence of water is disclosed, the collagen having cross-linking structure. Artificial skin prepared by using this medical material as a wound-contacting layer (2) is also disclosed.

Cell-penetrable medical material and artificial skin

Medical material and prosthetic skin in which cells can invade

Porous polypropylene membrane and methods for production thereof

A method for the manufacture of a hollow fiber membrane by mixing polypropylene, an organic filler capable of uniformly dispersing in the polypropylene in a fused state and easily dissolving in an extractant being used, and a crystal seed forming agent. The resulting mixture, in a molten state, is discharged in the shape of a hollow fiber through an annular spinning nozzle and into contact with a liquid made of said organic filler or a compound similar thereto. This results in cooling and solidifying the hollow fiber, which is then forwarded into contact with an extractant incapable of dissolving polypropylene, to remove the organic filler and form the membrane.

Process for hollow fiber membrane for artificial lung

A porous polypropylene hollow fiber membrane of a circular cross section 150 to 300 .mu.m in inside diameter and 10 to 150 .mu.m in wall thickness for use in an artificial lung, which hollow fiber membrane is characterized by having an inner surface aperture ratio in the range of 10 to 30%, a porosity in the range of 10 to 60%, and an oxygen flux in the range of 100 to 1,000 liters/min.m.sup.2.atm. and inducing no leakage of blood plasma within 20 hours use in the external circulation of blood therethrough.

Hollow fiber membrane for an artificial lung

A container made of synthetic resin and provided at one portion thereof with at least one tightly closable opening, which container has on a surface thereof a continuous coating having a gas barrier characteristic comprising low permeability to oxygen and carbon dioxide by the plasma treatment reaction of a mixture of a silicon compound having the general formula I with a silicon compound having the general formula II: ##STR1## wherein m=1-5, n=1-5, R.sup.1 and R.sup.2 are C.sub.1 -C.sub.5 alkyl, C.sub.1 -C.sub.5 alkoxy or phenyl or OH.

Container made of synthetic resin and method for manufacture thereof

Growing community of inventors

Fuji, Japan

Ken Tatebe