Boston Scientific Scimed, Inc.

Boston Scientific Corporation

Ken Merdan

Scott Schewe

Barry J O'Brien

Rajesh Radhakrishnan

Jan Weber

Aiden Flanagan

Liliana Atanasoska

Torsten Scheuermann

Steven R Larsen

Timothy Samuel Girton

Young-Ho Song

Dennis A Boismier

Robert Herrmann

Yixin Xu

Michael Kuehling

Chandru Chandrasekaran

Anurag Singhal

Matt Shedlov

Mary Joe Timm

Rajesh Radhakishnan

Scott R Schewe

A medical device is provided with a porous region including a reservoir zone including a polymer and a protective zone between adjacent tissue and the reservoir zone that restricts the tissue from direct contact with the polymer.

Endoprostheses

An implantable medical device for releasing therapeutic agent having a medical device body and a plurality of reservoir-defining structures disposed on a surface of the body. A reservoir can be defined by the reservoir-defining structures and therapeutic agent may be located in the reservoir. A cover may extend over the reservoir so that the therapeutic agent is released from the reservoir when the medical device implanted. Methods for making the medical device may also include providing a medical device body, positioning a plurality of reservoir-defining structures on a surface of the body to form a reservoir, loading therapeutic agent into the reservoir, and covering the reservoir so that the therapeutic agent may release when the medical device is implanted. Alternatively, the reservoir may be covered with a cover and an opening formed in the cover so that the therapeutic agent may release when the medical device is implanted.

Medical devices for releasing therapeutic agent and methods of making the same

A bioerodible endoprosthesis erodes to a desirable geometry that can provide, e.g., improved mechanical properties or degradation characteristics.

Bioerodible endoprostheses and methods of making the same

An endoprosthesis includes a plurality of struts defining a flow passage. At least one strut includes (a) a body comprising a bioerodible material and having a thickness and (b) a coating overlying the body. The coating includes a plurality of regions that allow physiological fluids to contact a plurality of corresponding areas of the underlying body when the endoprosthesis is implanted in a physiological environment. The plurality of regions are sized and arranged so that the contacted areas of the body erode substantially through the body in the thickness direction while the coating remains on the body when the endoprosthesis is implanted in the physiological environment.

Bioerodible endoprosthesis

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Loretto, MN, United States of America

Ken Merdan