Nissan Chemical Industries Limited

Ken-ichi Toyama

Takeshi Mita

Eitatsu Ikeda

Mitsuaki Komoda

Manabu Yaosaka

Yuki Furukawa

Motoyoshi Iwasa

Kazushige Maeda

Yoshihide Masuzawa

Hotaka Imanaka

Yuji Moriyama

Kazutaka Matoba

Yukihiro Maizuru

Hiroto Matsui

Youko Yamada

There is provided a novel agent for controlling harmful arthropods or nematodes that are parasites and hygienic pests for animals. An ecto- or endo-parasiticide for mammals or the like comprising as active ingredient, one or more selected from substituted benzamide compounds of formula (1) or salts thereof: wherein Ais C&#x2014;Xor nitrogen atom, etc., Aand Aare C&#x2014;H, etc., Ais C&#x2014;H or nitrogen atom, etc., G is G-2a, etc., W is oxygen atom or sulfur atom, Xis halogen atom, trifluoromethyl, etc., Xis hydrogen atom, halogen atom, trifluoromethyl, etc., Xis hydrogen atom, halogen atom, etc., Yis hydrogen atom, halogen atom, methyl, etc., Ris trifluoromethyl, etc., Ris E-3a, etc., Ris hydrogen atom, etc., p is an integer of 0 to 2.

Parasite- and hygienic pest-controlling agent

There is provided a method for catalytic asymmetric synthesis of optically active isoxazoline compound and an optically active isoxazoline compound. A method for catalytic asymmetric synthesis of optically active isoxazoline compound of a formula (6) including reacting an &#x3b1;,&#x3b2;-unsaturated carbonyl compound of a formula (1) and a hydroxylamine in a solvent in the presence of a base by adding a chiral phase transfer catalyst. An optically active isoxazoline compound of a formula (13) that can be synthesized by the method. 

Method for catalytic asymmetric synthesis of optically active isoxazoline compound and optically active isoxazoline compound

An isoxazoline-substituted benzamide compound of formula (1) or a salt thereof: wherein A, Aand Aindependently of one another are carbon atom or nitrogen atom, G is benzene ring, etc., W is oxygen atom or sulfur atom, etc., X is halogen atom, C-Chaloalkyl, etc., Y is halogen atom, C-Calkyl, etc., Ris &#x2014;CH&#x2550;NOR, &#x2014;C(O)OR, &#x2014;C(O)NHR, phenyl substituted with (Z), D-14, D-52, D-53, D-55 to D-59, etc., Ris C-Calkyl, etc., Ris C-Calkyl, etc., Ris hydrogen atom, &#x2014;C(O)R, &#x2014;C(O)OR, etc., Ris C-Calkyl, &#x2014;CHR, C-Calkynyl, &#x2014;C(O)R, &#x2014;C(O)OR, etc., further when Ris &#x2014;CH&#x2550;NOR, &#x2014;C(O)ORor &#x2014;C(O)N(R)R, Rmay be hydrogen atom, Ris C-Chaloalkyl, etc., Ris cyano, &#x2014;OR, etc., Ris C-Calkyl, C-Chaloalkyl, C-Calkoxy C-Calkyl, C-Calkylthio C-Calkyl, C-Ccycloalkyl, C-Calkenyl, etc., Ris C-Calkyl, C-Chaloalkyl, &#x2014;C(O)Ror &#x2014;C(O)OR, etc., Ris C-Calkyl or C-Ccycloalkyl, etc., Z is halogen atom, cyano, nitro, C-Calkyl, C-Calkoxy, etc., m is an integer of 0 to 5, n is an integer of 0 to 4, p1 is an integer of 1 to 5. The pesticide containing these compounds.

Isoxazoline-substituted benzamide compound and pesticide

There is provided a novel pest control agent, particularly an insecticide or miticide. A substituted isoxazoline compound of General Formula (1): where A, Aand Aindependently are CH or N, etc., X, Xand Xare independently are H, a halogen atom, etc., Yis H, etc., Ris &#x2014;C(O)R, &#x2014;C(S)R, Ris &#x2014;C(R)(R)&#x2014;S(O)R, &#x2014;C(R)(R)&#x2014;S(O)(R)&#x2550;NR, etc., Ris H, etc., Ris CF, CClF, etc., Ris H, etc., Ris H, etc., Ris H, etc., Ris Calkyl, etc., Ris H, etc., r is an integer of 0-2, t is an integer of 0 or 1; and a pest control agent comprising the compound or the salt thereof.

Substituted isoxazoline compound and pest control agent

A pesticide, particularly an insecticide or an acaricide, including a substituted isoxazoline compound of formula (1) or a salt thereof: wherein A, Aand Aindependently of one another are carbon atom or nitrogen atom, G is benzene ring, etc., L is &#x2014;N(R)&#x2014;, or &#x2014;CH(R)N(R)&#x2014;, etc., X is halogen atom, C-Chaloalkyl, etc., Y is halogen atom, C-Calkyl, etc., Ris &#x2014;C(O)R, &#x2014;C(O)OR, &#x2014;C(O)NHR, etc., Ris hydrogen atom, C-Chaloalkyl, &#x2014;C-Calkoxy C-Calkyl, cyano C-Calkyl, C-Calkenyl, C-Calkynyl, &#x2014;C(O)R, &#x2014;C(O)OR, etc., Ris C-Chaloalkyl, etc., m is an integer of 0 to 5, n is an integer of 0 to 4. The pesticide containing these compounds.

Isoxazoline compound and pesticide

An isoxazoline-substituted benzamide compound of formula (1) or a salt thereof: wherein A, Aand Aindependently of one another are carbon atom or nitrogen atom, G is benzene ring, etc., W is oxygen atom or sulfur atom, etc., X is halogen atom, C-Chaloalkyl, etc., Y is halogen atm, C-Calkyl, etc., Ris &#x2014;CH&#x2550;NOR, &#x2014;C(O)OR, &#x2014;C(O)NHR, phenyl substituted with (Z), D-14, D-52, D-53, D-55 to D-59, etc., Ris C-Calkyl, etc., Ris C-Calkyl, etc., Ris hydrogen atom, &#x2014;C(O)R, &#x2014;C(O)OR, etc., Ris C-Calkyl, &#x2014;CHR, C-Calkynyl, &#x2014;C(O)R, &#x2014;C(O)OR, etc., further when Ris &#x2014;CH&#x2550;NOR, &#x2014;C(O)ORor &#x2014;C(O)N(R)R, Rmay be hydrogen atom, Ris C-Chaloalkyl, etc., Ris cyano, &#x2014;OR, etc., Ris C-Calkyl, C-Chaloalkyl, C-Calkoxy C-Calkyl, C-Calkylthio C-Calkyl, C-Ccycloalkyl, C-Calkenyl, etc., Ris C-Calkyl, C-Chaloalkyl, &#x2014;C(O)Ror &#x2014;C(O)OR, etc., Ris C-Calkyl or C-Ccycloalkyl, etc., Z is halogen atom, cyano, nitro, C-Calkyl, C-Calkoxy, etc., m is an integer of 0 to 5, n is an integer of 0 to 4, p1 is an integer of 1 to 5. The pesticide containing these compounds.

There is provided a novel pesticide, particularly an insecticide or an acaricide. A substituted isoxazoline compound of formula (1) or a salt thereof: wherein A, Aand Aindependently of one another are carbon atom or nitrogen atom, G is benzene ring, etc., L is &#x2014;CH&#x2014;, &#x2014;C(CH)&#x2014;, &#x2014;CH(CN)&#x2014;, etc., X is halogen atom, C-Chaloalkyl, etc., Y is halogen atom, C-Calkyl, etc., Ris &#x2014;C(O)R, &#x2014;C(O)OR, &#x2014;C(O)NHR, etc., Ris hydrogen atom, C-Chaloalkyl, &#x2014;C-Calkoxy C-Calkyl, cyano C-Calkyl, C-Calkenyl, C-Calkynyl, &#x2014;C(O)R, &#x2014;C(O)OR, etc., Ris C-Chaloalkyl, etc., m is an integer of 0 to 5, n is an integer of 0 to 4. The pesticide containing these compounds.

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Funabashi, Japan

Ken-ichi Toyama