Bacterin International, Inc.

University of Utah Research Foundation

Kelly R Kirker

Gregory Juda

Nancy J Shelby

Steven M Scott

Benjamin P Luchsinger

Jesus Hernandez

Glenn D Prestwich

Yanchun Liu

Xiao Zheng Shu

Darrel L Holmes

Yi Luo

Darrel L Homes

Steven D Gray

Janice Gray, Legal Representative

Hao Li

A demineralized bone matrix is produced by a process in which a bone body is placed in a first processing solution comprising an acid to demineralize the bone body. The bone body is periodically removed from the first solution at specific time intervals to perform at least one test, such as a compression test, on a mechanical property of the bone body. When the test yields a desired result, the bone body is exposed to a second processing solution that is less acidic than the first, thus minimizing the exposure of the bone body to the harsh acidic conditions of the demineralization phase of the process.

Process for demineralization of bone matrix with preservation of natural growth factors

Described herein are crosslinked compounds useful in numerous treatments. Described herein are methods of making crosslinked compounds via (1) the oxidative coupling of two or more thiol compounds or (2) by the reaction between at least one thiol compound with at least one thiol-reactive compound.

Crosslinked compounds and methods of making and using thereof

Described herein are composites that inhibit or reduce adhesion between two or more tissues. Also described herein are methods of using the composites.

Anti-adhesion composites and methods of use thereof

Described herein are crosslinked compounds useful in numerous treatments. Described herein are methods of making crosslinked compounds via (1) die oxidative coupling of two or more thiol compounds or (2) by the reaction between at least one thiol compound with at least one thiol-reactive compound.

Growing community of inventors

Bozeman, MT, United States of America

Kelly R Kirker