Second Sight Medical Products, Inc.

Boston Scientific Neuromodulation Corporation

Pacesetter, Inc.

Advanced Bionics Corporation

Cardiac Pacemakers, Inc.

Other

Alfred E. Mann Foundation for Scientific Research

Doheny Eye Institute

Second Sight Products, Inc.

Kelly Hobart McClure

Robert Jay Greenberg

Arup Roy

Rongqing Dai

James Singleton Little

Richard Agustin Castro

Sumit Yadav

Neil Hamilton Talbot

Jordan M Neysmith

Matthew J McMahon

Chunhong Zhou

Scott M Loftin

Pishoy Maksy

Todd K Whitehurst

Brian V Mech

John J Reinhold

Avraham I Caspi

Sanjay Gaikwad

Gene A Bornzin

Jerry Ok

Kea-Tiong Tang

Mark Salman Humayun

Jordi Parramon

James R Thacker

Goran Nils Marnfeldt

Da-Yu Chang

James P McGivern

David Daomin Zhou

George Vamos

Gabriel A Mouchawar

Matthew Isaac Haller

Rafael Carbunaru

Dao Min Zhou

Alan Matthew Horsager

Susan McCord

Sheldon B Moberg

Daniel J Klosterman

Rudolph V Park

Timothy M Nugent

Peter Meilstrup

Joseph J Florio

James D Causey, Iii

Ione Fine

Scott Greenwald

Francesco Merlini

Donald Webber

Neha Vyas

Fatima Anaflous

Gregoire Cosendai

Xiaofan Wu

Eugene De Juan, Jr

Neha J Parikh

Timothy J Starkweather

James David Weiland

Junyu Mai

Brian Coley

David Marsh

Mohamed Khaldi

Jianing Wei

Walter P Little

Paul A Levine

John W Poore

Brian M Mann

Kristen N Jaax

Peter Boileau

Tom Xiaohai He

Robert Dai Ozawa

Ashish Ahuja

J Christopher Moulder

Jessy D Dorn

Jay Daulton

James Carl Makous

Lisa P Weinberg

Allan R Schwartz

Salomo Siilas Murtonen

Mark Humayan

Meredith Lee Anderson

Min-Yaug Yang

Mark Raymond Stultz

David W Adinolfi

Devyani Nanduri

Michael L Fister

Philip H Lee

Peter K Johnson

Hakan Hornell

Richard Augustin Castro

Sanjay Gaikwald

Richard A Castro

Peter Melistrup

The present invention consists of an implantable device with at least one package that houses electronics that receives input data or signals, and optionally, power, from an external system through at least one coil attached to the at least one package, processes the input data and delivers electrical pulses to neural tissue through at least one array of multiple electrodes that is/are attached to the at least one package. The invention, or components thereof, is/are intended to be installed in the head, or on or in the cranium, or on the dura, or on or in the brain.

Implantable device for the brain

The present invention is a system for detecting, tracking and recognizing human faces in a visual prosthesis. In a visual prosthesis, the input camera is always higher resolution than the electrode array providing percepts to the subject. It is advantageous to detect, track and recognize human faces. This information can be provided to the subject by highlighting the face in the visual scene, providing auditor or vibratory notice that a human face is in the visual scene, looking up the face in a database to identify and annunciate the name of the person in the visual scene, or otherwise communicate the identity of the person, like providing a custom vibratory pattern corresponding to known individuals (like custom ring tones associated with caller ID) or automatically zooming in on a face to aid the subject in identifying the face.

Face detection tracking and recognition for a visual prosthesis

In electrically stimulating neural tissue it is important to prevent over stimulation and unbalanced stimulation, which would cause damage to the neural tissue, the electrode, or both. It is critical that neural tissue is not subjected to any direct current or alternating current above a safe threshold. Further, it is important to identify defective electrodes, as continued use may result in neural damage and further electrode damage. The present invention presents system and stimulator control mechanisms to prevent damage to neural tissue.

Method and apparatus to provide safety checks for neural stimulation

Systems of techniques for controlling charge flow during the electrical stimulation of tissue. In one aspect, a method includes receiving a charge setting describing an amount of charge that is to flow during a stimulation pulse that electrically stimulates a tissue, and generating and delivering the stimulation pulse in a manner such that an amount of charge delivered to the tissue during the stimulation pulse accords with the charge setting.

Controlling charge flow in the electrical stimulation of tissue

The present invention is a fitting system with a graphical interface with specific interface screens for specific functions. Methods and devices for fitting a visual prosthesis are described. In one of the methods, threshold levels and maximum levels for the electrodes of the prosthesis are determined and a map of brightness to electrode stimulation levels is later formed. A fitting system for a visual prosthesis is also discussed, together with a computer-operated system having a graphical user interface showing visual prosthesis diagnostic screens and visual prosthesis configuration screens.

Visual prosthesis fitting

A visor for visual stimulation of visually impaired subjects is shown. The visor comprises a frame, a coil, a camera and a mounting system. A connector allows the coil to be positioned along a first direction. A sliding device allows the coil to be positioned along a second direction. Positioning of the visor on a subject's nose allows the coil to be positioned along a third direction. Positioning of the coil along the first, second or third direction is useful to maximize coupling RF coupling between the coil and an internal coil implanted on a subject wearing the visor.

Visual prosthetic apparatus for retinal stimulation

An implantable device having a biocompatible hermetic package made from a biocompatible electrically non-conductive substrate and a cover bonded to the substrate. In integrated circuit and passive circuits all bonded directly to the substrate.

Package for an implantable neural stimulation device

The present invention is a system for detecting, tracking and recognizing human faces in a visual prosthesis. In a visual prosthesis, the input camera is always higher resolution than the electrode array providing percepts to the subject. It is advantageous to detect, track and recognize human faces. Then information can be provided to the subject by highlighting the face in the visual scene, providing auditor or vibratory notice that a human face is in the visual scene, looking up the face in a database to state the name of the person in the visual scene, otherwise communication id like providing a custom vibratory pattern corresponding to known individuals (like custom ring tones associated with caller ID) or automatically zooming in on a face to aid the subject in identifying the face.

In electrically stimulating neural tissue it is important to prevent over stimulation and unbalanced stimulation which would cause damage to the neural tissue, the electrode, or both. It is critical that neural tissue is not subjected to any direct current or alternating current above a safe threshold. Further, it is important to identify defective electrodes as continued use may result in neural damage and further electrode damage. The present invention presents system and stimulator control mechanisms to prevent damage to neural tissue.

The disclosure relates to a flexible circuit electrode array comprising: a polymer base layer; metal traces deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; a polymer top layer deposited on said polymer base layer and said metal traces; and at least one support embedded in said array. The disclosure further relates to a flexible circuit electrode array comprising: a polymer base layer; metal traces deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; a polymer top layer deposited on said polymer base layer and said metal traces; and a folded flexible circuit cable connecting the electrode array with an interconnection pad. The disclosure further relates to a method of making a flexible circuit electrode array comprising: depositing a polymer base layer; depositing metal on said polymer base layer; patterning said metal to form metal traces; depositing a polymer top layer on said polymer base layer and said metal traces; heating said flexible circuit electrode array in a mold to form a three dimensional shape in said flexible circuit electrode array, embedding a support at least in the base layer, top layer or between the base and top layer, and/or folding a flexible circuit cable at least once connecting the electrode array with an interconnection pad on the array.

Flexible circuit electrode array with wire or film support

The present invention consists of an implantable device with at least one package that houses electronics that sends and receives data or signals, and optionally power, from an external system through at least one coil attached to the at least one package and processes the data, including recordings of neural activity, and delivers electrical pulses to neural tissue through at least one array of multiple electrodes that is/are attached to the at least one package. The device is adapted to electrocorticographic (ECoG) and local field potential (LFP) signals. The output signals provide control for a motor prosthesis and the inputs signals provide sensory feedback for the motor prosthesis. The invention, or components thereof, is/are intended to be installed in the head, or on or in the cranium or on the dura, or on or in the brain.

Cortical interface for motor signal recording and sensory signal stimulation

A visual prosthesis apparatus and a method for limiting power consumption in a visual prosthesis apparatus. The visual prosthesis apparatus comprises a camera for capturing a video image, a video processing unit associated with the camera, the video processing unit configured to convert the video image to stimulation patterns, and a retinal stimulation system configured to stop stimulating neural tissue in a subject's eye based on the stimulation patterns when an error is detected in a forward telemetry received from the video processing unit.

Visual prosthesis

Growing community of inventors

Simi Valley, CA, United States of America

Kelly Hobart McClure