Ajinomoto Co., Ltd.

Keizo Matsuda

Konosuke Sano

Koji Mitsugi

Naohiko Yasuda

Fumihide Tamura

Hidetsugu Nakazawa

Katsumi Sugiyama

Kazuhiko Yamada

Masanao Ozaki

Ichiro Noda

Emiko Shinohara

Kazushi Togo

Takehiko Ichikawa

A process for producing .alpha.-L-aspartyl-L-phenylalanine methyl ester or its hydrohalide, which comprises subjecting 3-benzyl-6-carboxymethyl-2,5-diketopiperazine to partial hydrolysis with a strong acid in a solvent mixture of methanol and water.

Process for producing .alpha.-L-aspartyl-L-phenylalanine methyl ester or

2-Amino-(2)-thiazoline-4-carboxylic acid is prepared by dehydrochlorinating S-(.beta.-carboxy-.beta.-chloroethyl) isothiourea by adding it to an aqueous medium maintained at a pH ranging from 5.5 to 7.5 with an alkali.

Process for producing 2-amino-(2)-thiazoline-4-carboxylic acid

A method for producing L-cysteine and/or L-cystine which comprises: A. holding 2-amino-thiazoline-4-carboxylic acid in an aqueous solution at a pH of 5 to 11 in the presence of an effective amount of enzyme produced by a microorganism; said enzyme being capable of converting the 2-amino-thiazoline-4-carboxylic acid to L-cysteine and/or L-cystine, and said microorganism being capable of growing in a medium containing 2-amino-thiazoline-4-carboxylic acid as a nitrogen source; and B. recovering the L-cysteine and/or L-cystine formed from said aqueous solution.

Method of producing L-cysteine and L-cystine

A decarboxylase in cells of Micrococcus strains converts tryptophan, phenylalanine, and substitution products thereof to the corresponding phenyl- and indolylethylamines. The enzyme can be recovered in pure state from the microorganisms, but cells and cell material are effective enzyme sources in the decarboxylation reaction.

Enzymatic method for producing aromatic ethylamines

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Kawasaki, Japan

Keizo Matsuda