Seedlings Life Science Ventures, LLC

Preva, LLC

Other

Iliad Biotechnologies, LLC

Seedings Life Science Ventures LLC

Keith Rubin

Michael R Cole

James M Sellers

Mathew S Cardinali

Ken Solovay

Michael Perlman

James H Layer

Sidney Perlman

Alex Desimone

Jon Buzzard

Klaus Lessnau

Stephen Jay Lowenstein

Steven Glazer

Haydn B Taylor

Timothy VanderMey

Kingston Mills

Bin Yan

Alfred A Desimone

Marina Lynch

Stephen M Zappala

Mathew Cardinali

Jim Sellers

James Layer

Timothy Vandermey

Michael Ellis Perlman

A nasal irrigation diagnostic assembly comprising an irrigation device including a fluid collection portion structured to retain a biological sample, in the form of waste solution from the nasal cavity resulting from irrigation. A detection member disposed on said irrigation device is exposed to the biological sample and is structured to determine the existence of at least one analyte within the biological sample of the waste solution. The detection member comprises a plurality of detection zones individually structured to analyze the biological sample upon engagement therewith, wherein said plurality of zones include at least a reaction zone and a detection zone, which respectively include reagents cooperatively and collectively formulated to detect the existence of the at least one analyte within biological sample of the waste solution. A control zone may also be included to indicate the intended operability of at least the detection member.

Nasal irrigation diagnostic assembly

Administering a live, attenuated-based vaccine to a subject at risk for developing a neurodegenerative disease featuring Aβ brain plaques can prevent or reduce the amount of Aβ brain plaques that would have developed in the subject without such treatment.

Treatment and prevention of neuropathology associated with neurodegenerative diseases

A system and accompanying assembly, of integrated or modular construction, for inflating and monitoring pressure within a retaining cuff including a housing having a pressure chamber connected in fluid communication with a fluid pressure source and a fluid communicating connection with the retaining cuff. Associated control circuitry includes a pressure sensor disposable in fluid communication with the pressure chamber and the retaining cuff, via the fluid communicating connection and structured to concurrently determine and monitor pressure within the pressure chamber and the retaining cuff. The control circuitry is cooperatively structured with the pressure sensor and other operative components to establish dynamic multilevel sampling capabilities, calibration parameters stored within the control circuitry prior to use and limited or single use capabilities of the assembly.

System and assembly for inflating and monitoring pressure within a retaining cuff

An assembly for nasal irrigation for the handheld irrigation of a user's nasal cavity comprising a housing with a refill chamber containing irrigating fluid, an applicator, an actuator for forcing irrigating fluid from the refill chamber through the applicator into the user's nasal cavity during operation, and a solution port for refilling the refill chamber. Some embodiments of the present invention may further comprise a system for nasal irrigation that includes the assembly for nasal irrigation or handheld irrigator, as well as a solution assembly structured for dispensing irrigating fluid to the handheld irrigator, a docking station for removably housing the handheld irrigator, a solution assembly and a refill control, including a check valve.

Nasal irrigation assembly and system

An assembly structured for concurrent irrigation and aspiration of a nasal cavity including a housing having a supply container disposed therein for the removable retention of irrigating fluid. A nasal applicator comprises first and second passages respectfully structured to deliver irrigating fluid to the nasal cavity and concurrently remove waste fluid therefrom. An activating assembly includes a plunger biased into a continuous pressure applying, dispensing relation to the irrigating fluid and a valve assembly is selectively disposable into an open position facilitating fluid communication between the supply container and the applicator for the delivery of the irrigating fluid therethrough into the nasal cavity. The activating assembly is further structured to create a negative pressure within the chamber which communicates with the second passage of the applicator to facilitate delivery of the waste fluid therefrom along a path of travel to an interior of the chamber.

Irrigation assembly

A assembly for nasal irrigation for the handheld irrigation of a user's nasal cavity comprising a housing with a refill chamber containing irrigating fluid, an applicator, an actuator for forcing irrigating fluid from the refill chamber through the applicator into the user's nasal cavity during operation, and a solution port for refilling the refill chamber. Some embodiments of the present invention may further comprise a system for nasal irrigation that includes the assembly for nasal irrigation or handheld irrigator, as well as a solution assembly structured for dispensing irrigating fluid to the handheld irrigator, a docking station for removably housing the handheld irrigator, a solution assembly and a refill control, including a check valve.

A stethoscope disinfection monitoring and reporting system structured and configured to track, monitor and report the cleaning, disinfecting, and/or sterilizing of the head portion of a stethoscope is presented. The system comprises a stethoscope cleaning assembly cooperatively structured and configured to clean the head portion of the stethoscope, for instance, via the application of a cleaning fluid or solution thereto. The system further comprises a monitoring device and a cooperatively structured and disposed reader assembly. The monitoring device may be unique to, or otherwise serve to identify, the stethoscope. The reader assembly is structured and disposed to detect, identify, and record data pertaining to the monitoring device and/or stethoscope upon cleaning the head portion, or otherwise upon disposition of the head portion into a cleaning relation with the stethoscope cleaning assembly.

Stethoscope disinfection monitoring and reporting system

An assembly structured to inflate a retaining or pressure cuff associated with an artificial airway tube such as an endotracheal and/or tracheotomy tube and concurrently monitor pressure therein including a casing having an interior pressure chamber. A pump assembly is movably connected to the casing and structured to force fluid flow to the retaining cuff through said pressure chamber. An indicator member is disposed within the casing, is visually accessible through casing window, and is variably positionable dependent on and indicative of existing pressure within the retaining cuff. The existing pressure within the pressure chamber is substantially equivalent to that within the retaining cuff thereby facilitating the variable position of the indicator member to indicate pressure within the cuff. A junction is disposed between the casing and an inflation lumen to the restraining cuff and is structured to allow disconnection between the casing and the lumen but prevent reconnection thereto.

Inflation and monitoring assembly for a pressure cuff of an endotracheal tube

Stethoscope cleaning assembly cartridge

Growing community of inventors

Fort Lauderdale, FL, United States of America

Keith Rubin