Cook Medical Technologies LLC

Cook Biotech, Inc.

Cook Regentec LLC

Keith Milner

Adam Shields

Kenneth Aaron Haselby

Sara Marie Sherman

Richard Swift

Steven Charlebois

Blayne A Roeder

Jarin A Kratzberg

Matthew S Huser

David Douglas Grewe

Mark Allen Magnuson

Charles Leland Baxter

James C Merk

Shyam Kuppurathanam

Therese J O'Day

William S Gibbons, Jr

Melissa Lonn

Seoggwan Kim

Lindsay Koren

Richard Earl Luedemann

Angela Rose Barnett

Kalub Hahne

Richard Hadley

Ram H Paul, Jr

William John Havel

Umesh H Patel

William Kurt Dierking

Frank J Fischer, Jr

Bhavin Shah

Duane D Blatter

Joshua Frye Krieger

Triona Campbell

Woong Kim

Rick Hadley

Jichao Sun

Brent A Mayle

Andrew P Isch

Brian D Choules

Dean R Puckett

Kevin Blum

Ralf Steiner

Reza Shirazi

Darin Voorhies

Rhonda Peck

Krista Gearhart

Oliver Bach

Frank J Fisher

Eric J Rodenberg

David G Grewe

Steven J Charlebois

Kenneth Haselby

Disclosed herein is a device for disrupting material in a body vessel and a method for making such a device. The device includes a plurality of arms disposed circumferentially about an axis. Each arm includes two blades; one sharper, and one blunter. The sharper blades are all oriented in the same direction, clockwise or counterclockwise, such that when the device is rotated in a first direction, the sharper blades engage the material, and in the other, the duller blades engage the material.

Device with sharp and blunt regions for removing occlusions

Described are peritoneal dialysis systems and methods that involve the use of crossflow filtration of a used dialysate withdrawn from the peritoneal space of a patient. The filtration forms a retentate containing amounts of an osmotic agent and a permeate containing amounts of water and nitrogen-containing waste products of the patient. The retentate, or a fraction thereof, can be returned to the peritoneal space of the patient to return osmotic agent to the patient. The permeate, or a fraction thereof, can be discarded to discard nitrogen-containing waste products of the patient.

Filtration system and process for peritoneal dialysis

The present invention provides, in certain aspects, medical graft products that incorporate multiple drug depots in and/or on the products. One such product is a sheet graft construct, for example for tissue support that includes a sheet graft material with a plurality of drug depots. The drug depots can be hardened deposits formed directly onto the sheet graft material and/or can be capable of eluting a drug for a minimum of 72 hours.

Drug eluting graft constructs and methods

A graft having a tubular body having a first end configured for attachment to a first vessel having a first compliance and second end configured for attachment to a second vessel having a second compliance different from the first compliance, and having a plurality of compressible chambers in the wall of the tubular body in which the chamber adjacent the first end of the tubular body is less compressible than the chamber adjacent the second end of the tubular body such that first end of the tubular body substantially matches the first compliance and the second end of the tubular body substantially matches the second compliance.

Vascular graft with compartments for compliance matching

Examples of a stent are provided with interlocking joints removably coupling adjacent axial stent segments. Mating elements forming the interlocking joints maintain engagement when the stent is in the radially compressed configuration, for example, during tracking of the stent to a treatment site of a body vessel, and become disengaged during radial expansion of the stent. When disengaged, the disconnected the axial stent segments remain discrete stent structures separated from one another along the point of treatment.

Stent with segments capable of uncoupling during expansion

A prosthesis is disclosed including an expandable frame having a first region and a second region coupled to one another. The first region includes a transition segment and a flex segment. The stent members of the transition segment have proximal and distal apices arranged in a peak-to-peak relationship with one another. At least a portion of proximal and distal apices of the transition segment remains uncoupled to one another. The flex segment includes a stent member having proximal and distal apices arranged in a peak-to-valley relationship with the transition segment. Longitudinal tie bars are intermittently coupled between apices the flex segment and the transition segment at coupling joints. The coupling joint is located where the proximal and distal apices of the stent members of the transition segment remain uncoupled to one another. The transition and flex segments may form an alternating pattern. A flareable proximal portion may be included.

Prosthesis with flexible stent

A graft for inducing helical blood flow, including a tubular body with fluid inflow and fluid outflow ends, and with inner and outer sidewalls. A lumen extends between the fluid inflow end and fluid outflow end. A compressible chamber is disposed between the outer sidewall and the inner sidewall. The compressible chamber has an incompressible seam that follows a substantially helical path around a longitudinal axis of the tubular body. When internal (e.g., blood) pressure increases on the inner sidewall, a vane element is formed that follows the substantially helical path around the longitudinal axis of the tubular body. The vane element may induce helical blood flow. The width of the compressible chamber may decrease in a compressed state (e.g., systole). The chamber may be filled with a predetermined amount of at least one of a gas, liquid, or vapor. The graft may have a second incompressible seam/vane.

Vascular graft with helical flow compliance compartments

A device for forming a fistula between blood vessels includes a tubular body having a central lumen, a flange attached to the tubular body and projecting outwardly from an outer body surface, and one or more vanes projecting inwardly into the lumen so as to induce helical flow in blood passed through the lumen between first and second vessels joined via the fistula.

Device for forming fistula between blood vessels, and method

A needle disclosed herein may include an elongate body extending between a proximal end and a distal end with a central longitudinal axis defined by the body, where the distal end includes a single sharp point along the central longitudinal axis and defining a distal end terminus three longitudinal fluted surfaces converging at the distal end terminus; and three longitudinal beveled cutting edges defining borders between the fluted surfaces and converging at the distal end terminus. Needle embodiments may include one or more ports open into and/or proximal of the fluted surfaces and communicating with one or more longitudinal needle lumens.

Tri-fluted vascular access needle

A cannula cut spiral flow inducing stent includes a plurality of spiral inducing flow diverters that each include a piece of sheet metal with a helically shaped flow surface. A proximal stent region, which includes a plurality of first struts, is joined to a proximal end of each of the spiral inducing flow diverters. A distal stent region, which includes a plurality of second struts, is joined to a distal end of each of the spiral inducing flow diverters. All of the first struts and all of the second struts share a cannula thickness, but the shaped pieces of sheet metal may have a lesser thickness.

Spiral flow inducing stent and canula cut method of making same

A multi-part medical implant device assembly for use in the surgical creation of an arteriovenous fistula is described herein, the implant device having an arterial section with an arterial lumen provided therein, a venous section with a venous lumen provided therein, and a connector section with a connecting lumen provided, the connector section serving to provide a fluid pathway from the arterial section to the venous section. The device may be formed of a top and a bottom portion, where the two-part assembly may facilitate surgical implantation.

Medical device and corresponding method of use for arteriovenous fistula creation

A perfusion device and a delivery system for repair of a damaged portion of a body vessel. Perfusion device can include a tubular body that is self-expandable, having a proximal portion, a distal portion, and an intermediate portion. One or more series of barbs can be disposed circumferentially along the intermediate portion. Barbs are capable of penetrating into the tunica intima and tunica media of said vessel wall upon insertion of said device into said body vessel, and not into said tunica adventitia. A graft can be associated with the tubular body. Graft has a proximal end and a distal end, and preferably extends entirely along a luminal wall of the tubular body. Graft may also extend along an exterior surface of the tubular body at the proximal and distal portions. Delivery devices for the perfusion implant and methods of delivering the perfusion implant are also provided.

Blood perfusion device

A drug delivery device is provided for directly treating a treatment site. The device allows body fluids to perfuse past the device while it is expanded to increase the amount of treatment time that is possible. The drug is delivered through a hollow helical tube that extends around a support structure. The hollow tube includes a series of lateral holes to allow the drug to directly reach the desired treatment site.

Site specific drug delivery device

The present embodiments provide an endoluminal prosthesis, such as a stent-graft, having a relatively low delivery profile. In one embodiment, the prosthesis comprises a membrane, and at least one stent having contracted and expanded states, where the stent is coupled to the membrane and maintains patency in the expanded state. The prosthesis further may comprise selectively oriented axial and/or circumferential fibers arranged at predetermined locations along the length and circumference of the prosthesis. An increased population density of the circumferential and/or axial fibers may be provided in areas in which the at least one stent portion is attached to the membrane, or in areas of higher physiological loads imposed upon the endoluminal prosthesis. Selectively orienting axial fibers and circumferential fibers at predetermined locations along the length and circumference of the prosthesis, but not continuously along the entire prosthesis, significantly reduces delivery profile due to the reduction in graft material.

Medical prostheses having bundled and non-bundled regions

Examples of a stent is provided with interlocking joints removably coupling adjacent axial stent segments. Mating elements forming the interlocking joints maintain circumferential and axial engagement when the stent is in the radially compressed configuration, for example, during tracking of the stent to a treatment site of a body vessel, and become disengaged during radial expansion of the stent. The length of mating elements may be sized as large as the strut width. When disengaged, the disconnected the axial stent segments remain discrete stent structures separated from one another along the point of treatment.

Growing community of inventors

West Lafayette, IN, United States of America

Keith Milner