Other

Advanced Csf Therapies, LLC

Seacoast Neuroscience, Inc.

Keith G Baker

John Pile-Spellman

Jae H Choi

Alexander Klose

Samuel S Macausland

Martin P Redmon

Mark T Kieras

A method for delivering drugs into cystic fluid, the method comprising injecting a drug delivery system (DDS) into a cystic fluid space at an injection site, the DDS comprising at least one therapeutic agent encapsulated in biodegradable polymers, applying ultrasonic energy proximal to the injection site, and controlling the at least one of buoyancy, delivery location, mixing, and dispersion of the DDS to a targeted area using the ultrasonic energy.

Methods and system for ultrasonic targeted drug delivery in cystic fluids, such as the cerebrospinal fluid, using buoyancy specific drug carriers

A vertical hydroponic system comprising a hollow cylindrical growing housing including a first end, a second end, and a peripheral surface having a plurality of apertures, the plurality of apertures having an external opening and an internal opening, the external opening located at a distance offset from the internal opening creating an angled surface extending between the external and internal opening, a spray nozzle located at the first end, a drain apparatus located at the second end, a container containing a liquid, a pump submerged in the liquid, a supply line extending from the pump to the spray nozzle, and a drain line extending from the drain apparatus to the container.

Vertical hydroponic system

The invention provides compositions and methods for treating a subject who has suffered from a central nervous system disorder. More particularly, the invention provides sustained polymeric drug delivery systems having a polymer particle, a therapeutic agent, and a buoyancy agent for direct delivery of therapeutic agents into the central nervous system.

Buoyant polymer particles for delivery of therapeutic agents to the central nervous system

A method for universally distributing a therapeutic agent, in an encapsulated form, to the brain of a subject using intrathecal administration, excluding the lumbar region, is described. Methods for treating stroke and/or Traumatic Brain Injury (TBI) are also described. The methods involve intrathecal administration into the cerebrospinal fluid of a subject, of a therapeutic agent in an encapsulated form. Pharmaceutical compositions intended for the amelioration of stroke and/or Traumatic Brain Injury (TBI) are also described. The pharmaceutical compositions comprise a therapeutic agent encapsulated in a pharmaceutically acceptable polymer, suitable for injection into the cerebrospinal fluid of a subject suffering from stroke and/or Traumatic Brain Injury (TBI).

Methods for universally distributing therapeutic agents to the brain

Wind energy conversion apparatus comprises vertical endless travelling belt means and a plurality of inter-spaced hydrodynamic foil members mounted thereon. Passage of fluid, i.e. wind, over the foil members creates lift forces thereon serving to drive the endless belt means about belt circulating parts. The foil members may have a fixed angle of incidence with respect to the belt runs i.e. between the circulating parts at the top and bottom of the endless belt means; or they may be of variable pitch. In one embodiment the belt means comprises two separate endless belts the foils are carried on arms which have pivotal connections with both belts; and a tension spring connects the belts. A belt circulating part, the lower wheel is coupled to a rotary load, an electric generator. Aerodynamic lift on the foils drives the belt and, by the spring connection, the belt and the rotary load. The foil angle of incidence is determined by the lift and the spring reaction.

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Rutledge, PA, United States of America

Keith G Baker