Trustees of the Colorado School of Mines

Keith Benjamin Neeves

David W M Marr

Charles D Eggleton

Kevin B Roth

Tonguc Onur Tasci

Abimbola Onasoga

Ryan R Hansen

The invention relates to a magnetic-field driven colloidal microbot that employs wall-based propulsion, method of forming the microbot and a method of using the microbot. The microbot can be formed in situ with the use of magnetic fields, and the magnetic fields can be used to translate the microbot to a specified location in a patient. The microbot does not depend on 'swimming' or flow currents within a patient to move, but instead can propel itself along a surface using a magnetic field. Once the magnetic field is removed, the microbot disassembles into colloidal particles.

Magnetic-field driven colloidal microbots, methods for forming and using the same

A microfluidic-based flow assay and methods of manufacturing the same are provided. Specifically, the microfluidic flow assay includes a substrate surface comprising lipid coated particles and microfluidic channels through which a blood product can flow. The lipid coated particles comprise functional molecules that can induce or inhibit the coagulation cascade.

Microfluidic flow assay and methods of use

A microfluidic system, device, and method are disclosed. The microfluidic system may include a first microfluidic channel and a second microfluidic channel, each of which are carrying one or more objects. There is an intersection between the first and second microfluidic channels where one or more objects from the first microfluidic channel impact one or more objects from the second microfluidic channel under hydrodynamic forces. The impact causes the objects to deform and the deformation of objects can be analyzed to determine properties of the object.

Optical alignment deformation spectroscopy

A microfluidic-based flow assay and methods of manufacturing the same are provided. Specifically, the microfluidic flow assay includes a micropatterned surface that induces clot formation and an array of microfluidic channels though which blood flows. The micropatterned surface contains two clotting stimuli, one for inducing platelet adhesion and another for inducing the coagulation cascade.

Growing community of inventors

Denver, CO, United States of America

Keith Benjamin Neeves