Ocera Therapeutics, Inc.

Other

Ucl Business Plc

Freudenberg Oil & Gas, LLC

Anderson Scientific

Keith Anderson

Peter Manini

Stephen William Watt

Jim Behling

Christine Henderson Dougan

Attilia Figini

Rajiv Jalan

James Smith

James Kevyn Smith

Patrick Rawls

Sebastian Ospina

Nagarjuna Jillella

Ian Smitham

An annular dual barrier seal includes a pair of axially extending inner seal lips and a pair of axially extending outer seal lips, the pair of inner seal lips are connected to the pair of outer seal lips by a radially outwardly extending web portion. The pair of inner seal lips extend axially by a first dimension and the pair of outer seal lips extend axially by a second dimension which is greater than the first dimension. The pair of inner seal lips have a sealing surface that is one of partially toroidal and partially elliptical and that engage the radially inwardly facing first sealing surface and the pair of outer seal lips have a sealing surface that is one of partially toroidal, partially elliptical and conical.

Dual barrier seal

Disclosed herein are methods of treating and/or preventing portal hypertension and/or restoring liver function using L-ornithine phenylacetate.

Treatment of portal hypertension and restoration of liver function using L-ornithine phenylacetate

Disclosed herein are forms of L-ornithine phenyl acetate and methods of making the same. A crystalline form may, in some embodiments, be Forms I, II, III and V, or mixtures thereof. The crystalline forms may be formulated for treating subjects with liver disorders, such as hepatic encephalopathy. Accordingly, some embodiments include formulations and methods of administering L-ornithine phenyl acetate.

L-ornithine phenyl acetate and methods of making thereof

Disclosed herein are processes for making L-ornithine phenyl acetate. The process may include, for example, intermixing a halide salt of L-ornithine with silver phenyl acetate. The process may also include forming a phenyl acetate salt in situ. The present application also relates to various compositions obtained from these processes, including crystalline forms.

Methods of making L-ornithine phenyl acetate

Disclosed herein are processes for making L-ornithine phenyl acetate. The process may include, for example, inter-mixing a halide salt of L-ornithine with silver phenyl acetate. The process may also include forming a phenyl acetate salt in situ. The present application also relates to various compositions obtained from these processes, including crystalline forms.

Disclosed herein are crystalline forms of L-ornithine phenyl acetate and methods of making the same. The crystalline form may, in some embodiments, be Forms I, II, III and V, or mixtures thereof. The crystalline forms may be formulated for treating subjects with liver disorders, such as hepatic encephalopathy. Accordingly, some embodiments include formulations and methods of administering L-ornithine phenyl acetate.

An antenna array for receiving microwave signals is provided that is particularly designed for use in television receive only (TVRO) satellite earth stations. The array comprises a plurality of identically-directed microwave antenna elements arranged in a plane perpendicular to their common primary receiving direction. Each antenna element includes an integral low-noise amplifier (LNA). Outputs of the LNAs are combined to produce a composite output signal which provides maximum response to microwave radiation arriving from the common primary receiving direction of the elements and null responses to microwave radiation arriving from particular other directions. The array includes means for rotating the elements about an axis parallel to the common primary receiving direction. Such rotation effectively adjusts the angle between the primary receiving direction of the array and a null-response direction disposed in a plane perpendicular to the plane of the array. Interfering microwave signals or noise emanating from a source located in an angular direction that is slightly different from the primary receiving direction of the array can thereby be adjustably nullified by rotating the array about its primary receiving direction axis.

Microwave receiving antenna array having adjustable null direction

A simplified current-tuned bipolar junction transistor oscillator is provided that is especially adapted for low power applications. The oscillator hereof utilizes the diffusion capacitance of the transistor's forward-biased base-emitter junction together with an inductance connected directly across the transistor's base-collector junction as reactive elements in the oscillator's frequency determining network. The transistor's base-collector junction is operated at zero volts bias thereby insuring that its depletion capacitance is fixed. The input current to the emitter is varied to change the base-emitter diffusion capacitance thereby adjusting the oscillator's frequency of oscillation.

Current-tuned transistor oscillator

A quadrature detector circuit for demodulating frequency modulated information is provided that is particularly designed for use in television receive only (TVRO) satellite communication video receivers. The bandwidth restrictions of conventional quadrature detector circuits are eliminated by substituting a simple ferrite bead for the usual parallel capacitor, inductor, resistor combination heretofore required in quadrature detectors. The quadrature detector hereof produces a higher level of video output, improved linearity, and better selectivity, as compared to conventional quadrature detector circuits. Moreover, the quadrature detector hereof reduces circuit complexity, and decreases material costs and production time.

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San Diego, CA, United States of America

Keith Anderson