Asahi Kasei Medical Co., Ltd.

Keitaro Matsuyama

Naoki Morita

Teruhiko Oishi

Hiroshi Tajima

Toshinori Koizumi

Makoto Ozeki

Yusuke Tokimizu

A blood purifier includes a porous molded body; exhibits an excellent blood compatibility wherein platelet adherence is inhibited and exhibits a good cytokine adsorption capacity and a low pressure loss before and after blood treatment; and can be safely used. A blood purifier includes a main vessel and a porous molded body housed in the main vessel. The porous molded body contains a hydrophobic polymer and a hydrophilic polymer. The amount of low-melting-point water per 1 g of dry weight of the porous molded body is 0.12 g to 2.00 g. The contact change ratio for the porous molded body is 0% to 0.2%. The ratio L/D is 1.00 to 2.30 where, for the region taken up by the porous molded body in the main vessel, L is the length in the flow direction and D is the circle-equivalent diameter of the cross section in the direction perpendicular to the flow direction.

Blood purifier

A blood purification device includes a porous molded body containing an inorganic ion-adsorbing material and is characterized by the following: the concentrations of Mg, Al, Ti, V, Cr, Mn, Fe, Ni, Cu, Zn, Ga, Rb, Sr, Y, Zr, Mo, Ru, Ag, Cd, Sn, Cs, La, Pr, Sm, Gd, Tb, Ta, Au, Tl, Co, In, and Bi are each 0.1 ppb or less and the concentrations of Ba, Nd, Pb, And Ce are each 1 ppb or less in a physiological saline solution for injection both three months and six months after said physiological saline solution for injection is sealed in the blood purification device; and the number of fine particles having a size of 10 μm or more is 25 or less and the number of fine particles having a size of 25 μm or more is 3 or less in 1 mL of the physiological saline solution for injection.

Blood purification device and method for producing same

Provided is a blood purification device including a porous molded body that has a high phosphorus adsorption capacity and that can be used safely. A blood purification device includes a porous molded body containing an inorganic ion-adsorbing material and is characterized by the following: said blood purification device satisfies the relationship B=&#x2212;0.02 A+2.175&#xb1;0.185 (74&#x2264;A&#x2264;94) when the moisture content of the porous molded body is denoted by A and the bulk density is denoted by B; and the number of fine particles having a size of 10 &#x3bc;m or more is 25 or less and the number of fine particles having a size of 25 &#x3bc;m or more is 3 or less in 1 mL of a physiological saline solution for injection both three months and six months after said physiological saline solution for injection is sealed in the blood purification device.

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Tokyo, Japan

Keitaro Matsuyama