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Shimadzu Corporation

Keisuke Toyama

Shigeki Kajihara

Sadamu Tomita

Shunichi Amari

Shiro Ikeda

A biosignal measuring apparatus for measuring, with a plurality of sensors, minute biosignals generated from bioelectric current sources in a region of a patient to be diagnosed. The apparatus includes a signal decomposer for decomposing detection signals provided by the plurality of sensors into a plurality of independent components, a noise component remover for determining noise components among the independent components based only on states of the independent components, and removing the noise components, a signal restorer for deriving restored detection signals from respective non-noise independent components, and a signal analyzer for determining an intracerebral activity corresponding to each independent component of each of the restored detection signals. After removing independent components determined to be noise components by the independent component analysis technique, a detection signal is separately restored for each information source from the remaining non-noise independent components. Thus, without requiring separate magnetic sensors exclusively for detecting noise, restored magnetism detection signals sufficiently stripped of noise components for the purpose of biosignal analysis are obtained with ease only from the signals acquired with biosignal measuring sensors.

Biosignal measuring method and apparatus

A technique for accurately determining states of bioelectric currents occurring in particular positions in a site of interest of a patient. Transfer functions between the particular positions and each magnetic sensor are derived from a positional relationship between the site of interest and each magnetic sensor. Weight coefficients are computed from an inverse matrix obtained by adding a predetermined value to a matrix of the transfer functions, and virtual biomagnetism information obtained virtually by bioelectric currents set to the particular positions. Enhanced biomagnetism information with only the biomagnetism from the particular positions enhanced is acquired by superposing the weight coefficients of measured biomagnetism information. Based on this enhanced biomagnetism information, states of bioelectric currents occurring in the particular positions are determined accurately.

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Kyoto, Japan

Keisuke Toyama