Toyama Chemical Co., Ltd.

Keisuke Tohdo

Kazuya Hayashi

Junichi Mitsuyama

Katsuji Ojima

Kazuto Kunitani

Kozo Hori

Noriyuki Okujo

An arylamidine derivative represented by a general formula described below or a salt thereof has an excellent antifungal action and high safety, and it is useful as an antifungal agent with good pharmacokinetics and pharmacodynamic properties wherein X represents an unsubstituted or substituted lower alkylene or alkenylene group; Grepresents an oxygen atom, a sulfur atom, or an imino group; Grepresents a carbon atom or a nitrogen atom; Rrepresents at least one group selected from the group consisting of a hydrogen atom, a halogen atom, and unsubstituted or substituted alkyl, cycloalkyl and alkoxy groups; Rrepresents an unprotected or protected or unsubstituted or substituted amidino group; and Rrepresents a substituted amino or substituted cyclic amino group, or the like.

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Toyama, Japan

Keisuke Tohdo