Kyowa Hakko Kirin Co., Limited

Keisuke Kimpara

Yuichi Fukuda

Takeshi Takahashi

Yoshisuke Nakasato

Nobuyoshi Amishiro

Toshimi Kanai

Hisashi Tagaya

Motoya Mie

The present invention provides a nitrogen-containing heterocyclic compound or a pharmaceutically acceptable salt thereof having an inhibitory effect on the production of kynurenine, represented by formula (I): 

Nitrogen-containing heterocyclic compound having inhibitory effect on production of kynurenine

Provided is a kynurenine production inhibitor comprising a nitrogen-containing heterocyclic compound represented by formula (I): (wherein Rand Rmay be the same or different and each represent a hydrogen atom or the like, Gand Gmay be the same or different and each represent a nitrogen atom or the like, X represents formula (III): (wherein mand mmay be the same or different and each represent an integer of 0 or 1, Y represents an oxygen atom or the like, and Rand Rmay be the same or different and each represent a hydrogen atom or the like),Rrepresents optionally substituted lower alkyl or the like, Rrepresents a hydrogen atom or the like, and Rrepresents optionally substituted lower alkyl or the like), and the like.

Kynurenine production inhibitor

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Tokyo, Japan

Keisuke Kimpara