Sony Corporation

Fuji Jukogyo Kabushiki Kaisha

Taiyo Yuden Co., Ltd.

Kioritz Corporation

Perseus Proteomics Inc.

The University of Tokyo

Honda Motor Co., Ltd.

Nippon Piston Ring Co., Ltd.

Sanyo Special Steel Co., Ltd.

Showa Kiki Sangyo Kabushiki Kaisha

Keisuke Ishii

Akira Nagashima

Katsushi Kouda

Takayuki Hattori

Yoko Kayukawa

Tadashige Kondo

Katsuyuki Mitomo

Takashi Asai

Motoaki Etoh

Keiko Katsumi

Tadashi Matsuura

Nobuharu Murashima

Hisamitsu Shizuno

Hiroyuki Aburatani

Hitoshi Taguchi

Kentaro Fujii

Hiroshi Onishi

Mamoru Kugumiya

Fumiko Nomura

Lilin Zhang

Yuto Yamato

Hikaru Tanoue

Aya Sakamoto

Yoshiyuki Kamata

Isao Watanabe

Noriaki Takagi

Shin Miyashita

Masaki Saito

Toshiyuki Sawada

Kenji Nagashima

Kohtaro Amano

Koji Izumi

Hiroshi Oshige

Taku Yaegashi

Tomoki Okita

Susumu Miyashita

Kiyohide Sumi

Hiroyuki Hasegawa

Yuichi Kaneda

Satoshi Ikemi

Yuichi Ando

Yoshinori Sugiyama

Yukio Sudo

Hidetoshi Nakanishi

Hirotaka Ohno

Shin Nishiura

Seisuke Takaki

Ei Igarashi

Katsuhiko Ohno

Hibiki Yoshikawa

Manabu Sudo

Katuhiko Ohno

Yoshimasa Kitamura

Kyosuke Shimazaki

A multilayer ceramic capacitor includes a ceramic body including an electrode-stacked portion having first and second internal electrodes that are alternately stacked along a first axis direction, wherein the first internal electrodes include a first inner-layer internal electrode and a first outer-layer internal electrode that is absent at and adjacent to a position corresponding to at least one of four corners of the first inner-layer internal electrode, the second internal electrodes include a second inner-layer internal electrode and a second outer-layer internal electrode that is absent at and adjacent to a position corresponding to at least one of four corners of the second inner-layer internal electrode, and the electrode-stacked portion includes a pair of outer layer portions where the first and second outer-layer internal electrodes are stacked, and an inner layer portion positioned between the outer layer portions and where the first and second inner-layer internal electrodes are stacked.

Multilayer ceramic capacitor

A ceramic electronic device includes a multilayer structure having a substantially rectangular parallelepiped shape, a first cover layer, and a second cover layer that is provided on a second end of the multilayer structure in the stacking direction, a main component of the second cover layer being ceramic, a porosity of the second cover layer being higher than that of the first cover layer. Q=(A+B)/2C×100(%) is 0.5% or more and 1.6% or less, when, at an interface of the second cover layer on a side of the first cover layer, two heights of curvature portions of both ends of the interface are respectively a height A and a height B, and a shortest height from the first cover layer to the second cover layer is a height C.

Ceramic electronic device and manufacturing method of the same

A ceramic electronic component includes a multilayer chip including a multilayer structure, which includes ceramic dielectric layers and internal electrode layers that are alternately stacked, and cover layers respectively disposed on top and bottom faces of the multilayer structure in a first direction in which the dielectric layers and the internal electrode layers are alternately stacked, wherein each of the cover layers includes a relatively high porous section and a first relatively less porous section having a pore ratio less than a pore ratio of the relatively high porous section, the relatively high porous section laterally spreading and spanning an entire length of the cover layer in a second direction orthogonal to the first direction, the pore ratio of the relatively high porous section being 1% or greater, the first relatively less porous section being interposed between the relatively high porous section and the multilayer structure.

Ceramic electronic component and method of manufacturing the same

A multi-layer ceramic capacitor having a weight of 8 mg or more includes a capacitance forming unit and a protective unit. The capacitance forming unit includes internal electrodes that are laminated in a first direction and includes end portions, positions of the end portions in a second direction orthogonal to the first direction being aligned with one another within a range of 0.5 &#x3bc;m in the second direction. The protective unit covers the capacitance forming unit in the first direction and the second direction and includes an outer surface, a shortest distance between the outer surface and the end portion of an outermost layer in the internal electrodes in the first direction exceeding 10 &#x3bc;m.

Multi-layer ceramic capacitor

Camera

Provided is a valve seat insert made of an iron-base sintered alloy, in which a base matrix part that includes a base matrix phase and hard particles, has a base matrix part composition containing, in % by mass, 0.5%-2.0% of carbon and 10%-70% in total of one kind or two or more kinds selected from nickel, cobalt, chromium, molybdenum, vanadium, tungsten, manganese, silicon and sulfur, with the balance being iron and unavoidable impurities, and Co-base hard particles having a composition containing, 1.0% or less of C, 25%-50% of Mo, 5%-15% of Cr, Si as an impurity in a content adjusted to be 0.3% or less, with the balance being Co, and having a Vickers hardness of 500 to 1,500 HV, are dispersed as hard particles in the base matrix phase in an amount of 10%-60% by mass with respect to the total amount of the valve seat insert.

Valve seat insert for internal combustion engine having excellent wear resistance

It is an object of the present invention to provide a drug conjugate comprising an anti-CDH3 antibody that efficiently kills cancer cells expressing CDH3. According to the present invention, there is provided an immune complex formed by binding an antibody against CDH3 or a fragment thereof having CDH3 binding ability to a chemotherapeutic agent.

Drug conjugate comprising anti-CDH3 (P-cadherin) antibody

The present invention provides an anti-CDH3 humanized antibody having lower immunogenicity, and an anti-CDH3 humanized antibody drug conjugate having the aforementioned anti-CDH3 humanized antibody. The present invention provides a conjugate of an anti-CDH3 humanized antibody and a drug by conjugating a drug having cytotoxicity to an anti-CDH3 humanized antibody having complementarity determining region sequences derived from the heavy chain variable region of an antibody produced by cells having Accession No. NITE BP-1536, and complementarity determining region sequences derived from the light chain variable region thereof, and which also comprises a heavy chain human subgroup III consensus framework sequence or a human germline sequence selected under optimal alignment as a framework region sequence of the heavy chain variable region, and a light chain human &#x3ba; subgroup I consensus framework sequence or a human germline sequence selected under optimal alignment as a framework region sequence of the light chain variable region.

Anti-CDH3 humanized antibody, drug conjugate thereof, and use thereof

It is an object of the present invention to provide an anti-cadherin antibody having a high internalization capacity and provide an anti-cadherin antibody-drug conjugate that effectively kills cadherin-expressing cancer cells with the use of such antibody. The present invention provides an anti-cadherin antibody which recognizes a cadherin domain 1 (EC1) of cadherin and exhibits a high internalization capacity.

Anti-CDH3 antibody having high internalization capacity

It is an object of the present invention to provide an anti-cadherin antibody having high antibody-dependent cellular cytotoxicity. The present invention provides an anti-cadherin antibody, which recognizes any one of an upstream region of EC1, a cadherin domain 4 (EC4) and a cadherin domain 5 (EC5), wherein an antibody-dependent cellular cytotoxicity at an antibody concentration of 1 &#x3bc;g/mL is 30% or more.

Highly effective anti-cadherin antibody for induction of antibody-dependent cellular cytotoxicity in vivo

Data is shared between a vehicle mounted navigation device and a vehicle mounted user interface device and among a plurality of vehicle mounted user interface devices. In a first location free display that allows a plurality of users to separately have access to the navigation device, external data obtained from the navigation device or from another location free display and its own user data are saved and managed, and shared with the navigation device and the another location free display. It is possible to utilize the external data not owned by itself or the user data of another person with the navigation device or the another location free display and perform a navigation process in an inner space of the vehicle efficiently.

Vehicle mounted user interface device and vehicle mounted navigation system

Display devices are connected with a content server mounted inside a vehicle by a wireless communication technology as stipulated in IEEE802.11b. The content server and display devices share common keys (encryption key and corresponding decryption key) acted on by key creation information consisting of information about the vehicle. The content server reads out stored contents according to requests from the display devices. The read contents are then encrypted using the encryption key shared with the display devices and sent to the display devices. The invention can be applied to a wireless communication system consisting of devices which communicate data by wireless communication technology within the vehicle.

In-vehicle communication system and method therefor, in-vehicle communication terminal, communication method therefor, program recording medium, and program

Growing community of inventors

Tokyo, Japan

Keisuke Ishii