Proterial, Ltd.

Daiichi Sankyo Company, Limited

Sankyo Company, Limited

Daiichi Sankyo Europe Gmbh

Hitachi Astemo Ltd.

Hitachi Astemo Electric Motor Systems, Ltd.

Bioinvent International Ab

Keisuke Fukuchi

Shu Takahashi

Takehiro Hirai

Toshinori Agatsuma

Shoji Yamamoto

Masanori Sagawa

Reimar Abraham

Masato Amano

Kayoko Nanai

Kimihasa Ichikawa

Kozo Yoneda

Yusuke Totoki

Yukio Ikeda

Yuta Sugiyama

Kenji Murakami

Takeshi Takizawa

Kimihisa Ichikawa

Toshiaki Ohtsuka

Tatsuji Matsuoka

Ichiro Watanabe

Atsushi Urano

Kenji Hirotani

Masashi Yokoi

Junjie Shen

Mitsuhiro Yazawa

Shinko Hayashi

Johannes Bange

Tanja Lange

A resistor includes a resistor main body, and a resin portion covering the resistor main body. The resin portion includes a radiation fin.

Resistor

A resistor is composed of a resistor body part and a molded resin in which the resistor body part is embedded. The molded resin includes a base resin and a filler that is higher in thermal conductivity than the base resin.

Resistor and its manufacturing method

A physical quantity detection device is provided with first and second retainers arranged to sandwich a wire, and a physical quantity sensor fixed to the wire by the first and second retainers. The physical quantity of the wire is detected by the physical quantity sensor, and the first and second retainers are fixed to the wire by being locked with each other.

Physical quantity detection device

A wiring component with physical quantity sensor is provided with a plurality of electric wires, a physical quantity sensor for detecting a physical quantity of the plurality of electric wires, an electric wire holding member including an intervening portion interposed between the plurality of electric wires, and a holder holding the physical quantity sensor. The electric wire holding member includes a protrusion protruding from the intervening portion in a direction perpendicular to an arrangement direction of the plurality of electric wires, and aligning the holder in longitudinal directions of the plurality of electric wires by the protrusion. The holder includes an electric wire engaging portion being engaged with at least one of the plurality of electric wires.

Wiring component with physical quantity sensor

A wiring component with temperature sensor includes an electric wire, a temperature sensor including a detection unit configured to detect temperature of the electric wire and a plurality of lead wires, and a plurality of connector pins respectively connected to the plurality of lead wires. The electric wire, the temperature sensor and the plurality of connector pins are collectively held by a holder made of a resin. The holder includes a connector housing member configured to hold the plurality of connector pins and a molded resin member covering a portion of the connector housing member.

Wiring component with temperature sensor

A physical quantity sensor-fixing structure includes a holder holding a physical quantity sensor including a detection unit to detect a physical quantity and a plurality of lead wires connected to the detection unit. The holder fixes the physical quantity sensor to a plurality of conductive support members to be respectively connected to the plurality of lead wires. The holder includes a main body member including a housing portion to house at least a portion of the physical quantity sensor, and a lid member covering at least a portion of the housing portion.

Physical quantity sensor-fixing structure

A surge suppression device includes a plurality of series circuits each of which is composed of a resistor and a capacitor, a case in which a plurality of the resistors and a plurality of the capacitors are placed, wherein respective ends of the plurality of series circuits on the capacitor side are electrically connected to each other via a connection electrode provided on the case. A motor wiring component includes a plurality of conductive wires connected to stator coils of the motor, wiring terminals that are provided at ends of the plurality of conductive wires on a side opposite to the side connected to the stator coils and are connected to electrodes of a terminal block, and the surge suppression device.

Surge suppression device and motor wiring component

A temperature sensor detects temperatures of at least two distribution lines and includes a temperature detection unit and a protection member that covers the temperature detection unit. The protection member is provided with a first abutting surface that has a concave shape corresponding to an outer shape of a first distribution line and is in contact with the first distribution line and a second abutting surface that has a concave shape corresponding to an outer shape of a second distribution line and is in contact with the second distribution line.

Temperature sensor, power distribution component having the same, and motor having power distribution component

An object of the present invention is to provide a novel anti-CD147 antibody exhibiting potent antitumor efficacy and having excellent safety. Another object of the present invention is to provide a pharmaceutical product comprising such an antibody. Another object of the present invention is to provide a method for treating tumors using the antibody or the pharmaceutical product, for example. The present invention provides a CD147-specific antibody that activates CD147 and exhibits high antitumor efficacy. The present invention provides the anti-CD147 antibody that exhibits high antitumor efficacy independent of effector functions. The present invention provides a pharmaceutical composition comprising such an anti-CD147 antibody. The present invention provides a method for treating tumors using such an anti-CD147 antibody and/or pharmaceutical composition.

Anti-CD147 antibody

A motor wiring member configured to supply three-phase alternating current to a motor includes conductive wires, each of which has a connecting portion being provided at one end and being configured to be connected to a coil end of a stator of the motor, a terminal being provided at an other end of each conductive wire and being configured to be connected to an electrode of a terminal block, and a surge suppression section being configured to suppress an overvoltage from being applied to the motor. The surge suppression section includes three series circuits, each of which includes a resistor and a capacitor. One ends of the three series circuits are electrically connected to the conductive wires of respective phases, and other ends of the three series circuits are electrically connected to each other. The surge suppression section is provided along with the conductor wires near the terminal and is located between the terminal and the connecting portion.

Motor wiring member

The present invention relates to the medical use of antibodies against the FGF receptor 4 (FGFR4) combined with Sorafenib, in particular for the prevention or treatment of hyperproliferative diseases associated with FGFR expression, overexpression or hyperactivity.

Combination of human anti-FGFR4 antibody and Sorafenib

The present invention relates to novel antibodies against the FGF receptor 4 (FGFR4) and to the medical use thereof, in particular for the diagnosis prevention or treatment of diseases associated with FGFR expression, over expression or hyperactivity.

Human anti-FGFR4 antibody

An antibody exhibiting antitumor activity that binds to B7-H3, a functional fragment of the antibody, a pharmaceutical composition that includes the antibody or the functional fragment, methods for making the antibody or the functional fragment, methods for treating a tumor using the antibody or the functional fragment, and polynucleotides encoding the antibody or the functional fragment.

Anti B7-H3 antibody

The present invention relates to a method of detecting cancer by use of an oncogene, a method of screening for an active compound useful to treat and/or prevent cancer, and a pharmaceutical composition for treatment and/or prevention of cancer. More specifically, the present invention provides a method of detecting cancer based on the expression of the human oculospanin gene as a marker and a pharmaceutical composition containing an antibody capable of specifically recognizing human oculospanin and having cytotoxic activity against cancer cells.

Growing community of inventors

Tokyo, Japan

Keisuke Fukuchi