Other

Kowa Company Limited

Keio University

Takeuchi, Tsutomu

Yoshimoto, Keiko

Keiko Yoshimoto

Tsutomu Takeuchi

Katsuya Suzuki

Kensei Tsuzaka

Kensei Tsuzuka

The present invention provides a prophylactic and/or therapeutic agent for inflammatory disease including a compound or a salt thereof, or a solvate thereof, the compound represented by a formula (1): [where each sign is defined as described in the description] as an active ingredient.

Prophylactic and/or therapeutic agent for inflammatory diseases which contains pyrrolopyrimidine compound as active ingredient

A method of screening a novel BAFF suppressor or inhibitor. More specifically speaking, a method which comprises adding a combination of TPA with ionomycin and/or an anti-CD3 antibody to a cultured human cell to thereby induce the production of BAFF by the cell; a method of screening a substance capable of suppressing the expression or activity of BAFF which comprises adding a test substance to a BAFF-production system prepared by adding a combination of TPA with ionomycin and/or an anti-CD3 antibody to a cultured human cell and measuring the expression amount and/or the activity of BAFF in the BAFF-production system; and a BAFF production inducer for a BAFF-producing cell which contains a combination of TPA with ionomycin and/or an anti-CD3 antibody.

Method of screening baff suppressor or inhibitor

Method of screening Baff suppressor or inhibitor

Growing community of inventors

Tokyo, Japan

Keiko Yoshimoto