Chugai Seiyaku Kabushiki Kaisha

Keiko Sano

Yasuyuki Sakai

Eiichi Miyauchi

Takashi Uchio

Satoshi Yasukawa

The present invention aims to provide an O/W type creams showing improved skin absorption and heat stability of maxacalcitol as an active ingredient. The present invention provides O/W type creams containing maxacalcitol in the oil phase and/or water phase, more specifically O/W creams containing maxacalcitol and an emulsifier wherein maxacalcitol exists in the oil phase as well as O/W creams wherein maxacalcitol exists in the water phase.

Creams containing vitamin D3 derivatives

The present invention aims to provide an O/W type cream showing improved skin absorption and heat stability of maxacalcitol as an active ingredient. The present invention provides O/W type creams containing maxacalcitol in the oil phase and/or water phase, more specifically O/W creams containing maxacalcitol and an emulsifier wherein maxacalcitol exists in the oil phase as well as O/W creams wherein maxacalcitol exists in the water phase.

The present invention aims to provide a lotion stably maintaining maxacalcitol and having excellent percutaneous absorption. The present invention provides lotions comprising maxacalcitol as an active ingredient and a nonionic surfactant as an additive, as well as lotions which further contains a polyhydric alcohol and a solubilizer as additives besides a nonionic surfactant.

Growing community of inventors

Tokyo, Japan

Keiko Sano