Meiji Co., Ltd.

Meiji Dairies Corporation

Keiko Morikubo

Masayuki Uchida

Seiko Narushima

Kaori Yoshida

Akihiro Nakajima

Shigeru Yamato

Hajime Ariga

Hirotsugu Uehara

Tomofumi Amano

An object of the present invention is to provide a simple method of detecting a protein in a liquid, which requires less labor or cost as compared with a conventional method. In the present invention, it has been found that coloring a protein by a color reaction specific to the protein, performing filtration using a filter which easily adsorbs a protein to concentrate the protein on the filter, and checking coloration allows for simply and easily detecting and measuring a protein. In addition, it has been found that filtering a protein using a filter, concentrating the protein on the filter, then coloring the protein by a color reaction specific to the protein, and checking the protein allows simply and easily detecting and measuring a protein.

Method for detecting protein

The present inventors conducted dedicated studies, and as a result discovered that propionic acid bacteria fermentation products have a preventive/therapeutic effect on functional gastrointestinal disorders in in vitro tests and tests using patients with irritable bowel syndrome, and completed the present invention. Specifically, the present inventors discovered, in in vitro tests, that the products have an effect of increasing the intestinal contraction frequency without changing the intestinal contractile force in a distal colon-specific manner. Moreover, effects of improving the defecation condition, general abdominal condition, and health-related QOL in patients with irritable bowel syndrome were also found. Furthermore, propionic acid bacteria fermentation products can be taken in large amounts. Therefore, the propionic acid bacteria fermentation products can be expected to have an effect of preventing/treating functional gastrointestinal disorders safely.

Prophylactic and/or therapeutic agent for functional gastrointestinal disorders

The present invention relates to a preventive and/or a therapeutic agent for inflammatory bowel diseases containing a fermentation product of a propionic acid bacterium as an active ingredient.

Preventive and/or therapeutic agent for inflammatory bowel diseases

Preventive and/or remedy for inflammatory bowel diseases

Growing community of inventors

Odawara, Japan

Keiko Morikubo