Nippon Flour Mills Co., Ltd

Yamanouchi Pharmaceutical Company Ltd.

Kyoto Eiyo Co., Ltd.

Keijiro Uchino

Hideki Nakashima

Hiroshi Ogawara

Naoki Yamamoto

Fukushi Hirayama

Hirokazu Yamamoto

Shigenobu Kadota

Akira Fukuchi

Masashi Hiramoto

Sachie Murakami

Takashi Mizuno

Masaya Iwamoto

An object of the present invention is to provide a method for producing afermented food in which a flavor and odor that are peculiar to algae are reduced while production of pheophorbide is suppressed. The method for producing afermented food according to the present invention can be achieved by using anegative in coliform bacteria count, and having a content of free pheophorbide equal to or less than 18 mg % and a viable general bacteria count equal to or less than 8000 cfu/mL, or using asubjected to a heat sterilization treatment to ferment thewith a baker's yeast. The baker's yeast is blended with theat a ratio of preferably 0.1 to 15% by weight. Further, the fermentation treatment is preferably carried out in the presence of glucose and a lactic acid bacterium.

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The present invention provides a reverse transcriptase inhibitor and an antiviral agent comprising at least one member selected from the group consisting of sulfated tyrosines and physiologically acceptable salts thereof as an effective component; and exhibiting less toxicity and a remarkable inhibitory effect against a reverse transcriptase existing in viruses as well as a remarkable anti-AIDS viral activity.

Reverse transcriptase inhibitors and antiviral agents

Sulfated tannins or salts thereof are herein disclosed. These compounds can be prepared by a method which comprises reacting tannin with a sulfonating agent under a basic condition. These compounds show antiviral activity and reverse transcriptase inhibitor, effects and can be used to treat patients infected with a variety of virus such as AIDS virus, herpesvirus, influenza virus or rhinovirus.

Sulfated tannins and their salts

Growing community of inventors

Kanagawa, Japan

Keijiro Uchino