Hisamitsu Pharmaceutical Company, Inc.

Keiichiro Tsurushima

Takaaki Yoshinaga

Tetsuro Tateishi

Yasuhisa Kose

Shinji Yamasoto

Seiichiro Tsuru

Kentaro Nakashima

Tetsuji Kuwahara

Yusuke Tanaka

Junichi Kubo

Masato Wakamatsu

Masafumi Ono

Kento Ichinohe

Masakazu Saeki

A method for producing an adhesive layer composition for producing a cooling sheet including a backing layer, an adhesive layer, and a liner layer, the method comprising the step of:

Method for producing adhesive layer composition for producing cooling sheet, method for producing cooling sheet, and cooling sheet

Disclosed is a patch comprising an adhesive layer on a backing layer, wherein the adhesive layer comprises lidocaine or a pharmaceutically acceptable salt thereof, propylene glycol, a rubber adhesive base and a terpene resin, wherein the content of the lidocaine or a pharmaceutically acceptable salt thereof in the adhesive layer in terms of free form is 2 mass % to 6 mass % with respect to the total mass of the adhesive layer, wherein the ratio of the mass of the lidocaine or a pharmaceutically acceptable salt thereof in terms of free form to the mass of propylene glycol in the adhesive layer is 1:0.6 to 1:1.8, and wherein the content of the terpene resin in the adhesive layer is 5 mass % to 18 mass % with respect to a total mass of the adhesive layer.

Lidocaine-containing patch

A gel patch comprising a plaster layer on a support, the plaster layer comprising a mixture of at least a neutralized polyacrylic acid, a poly(methyl acrylate/2-ethylhexyl acrylate) emulsion, and water, wherein the poly(methyl acrylate/2-ethylhexyl acrylate) emulsion is an emulsion having an evaporation residue of 57 to 61% by heating at or above the boiling point of the medium and is present in an amount of at least 2.5 times and preferably at least 3 times the mass of the neutralized polyacrylic acid.

Cataplasm and method for producing the same

A gel patch includes a base fabric, an adhesive layer, and a release liner in this order, wherein the adhesive layer contains a physiologically active substance, a water-soluble (meth)acrylic polymer, water, a surfactant, and poly(methyl acrylate/2-ethylhexyl acrylate), and the surfactant comprises a polyethylene glycol fatty acid ester or a polyoxyethylene sorbitan fatty acid ester.

Gel patch

A lidocaine-containing hydrogel patch comprising:

Lidocaine-containing hydrogel patch

Growing community of inventors

Tosu, Japan

Keiichiro Tsurushima