Sekisui Medical Co., Ltd.

Hamamatsu-photonics K.k.

Keigo Kohno

Motoki Morita

Masato Nishikawa

Kazuo Kotani

Mitsuaki Yamamoto

Mayumi Yoshida

Shinya Yokokawa

Daichi Susuki

Marie Asami

Shun Sakai

Kazunori Saito

Fusanori Kondo

Akira Nakajima

Kumiko Yuki

Shinya Okuyama

Kengo Sadamori

Kanako Itou

Kanako Azuma

Naoyuki Honda

Saori Nozaki

An immunochromatographic test strip that enables a specimen to sufficiently and quickly permeate into a sample application region within a test time, reducing variations in detection values of a test line. The test strip maintains consistent detection values even with whole blood specimens. The immunochromatographic test strip includes at least a sample application region, a development region, and a detection region, wherein the sample application region contains polyethylene glycol having a molecular weight of 15,000 to 700,000.

Immunochromatographic test strip and immunochromatographic detection kit

An optical measurement deviceincludes: a measurement unit; and a determination unit, wherein the determination unit calculates a difference value between the initial measurement value and the latter measurement value when the measurement value exceeds the first threshold value after the sample is held by the lateral flow test strip, determines that the sample is positive when the difference value exceeds a second threshold value set in advance, and determines that the sample is negative when the difference value is the second threshold value or less.

Optical measurement device and optical measurement method

To provide an immunochromatographic test device capable of accurate diagnosis even when an excess sample is introduced. Provided is the immunochromatographic test device consisting: a test strip; a lower housing including a plurality of support bases that support the test strip; and an upper housing including a dropping hole for dropping a sample into the test strip and a detection window in a direction in which the sample introduced from the dropping hole develops on the test strip, wherein a width of the support base that supports portion of the test strip exposed from the detection window is smaller than a width of the test strip, or wherein among the plurality of support bases, the width of the support base arranged on the lower housing between a position corresponding to the detection window and a position corresponding to the dropping hole is larger than the width of the test strip.

Immunochromatographic test device

A problem of the present invention is to provide an immunochromatographic test strip avoiding agglutination of colloidal gold while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a hemagglutinating agent and the colloidal gold conjugates as a detection reagent, and to provide immunochromatography using the test strip. To solve the problem, the present inventors reviewed the composition of the existing reagent itself from a completely different viewpoint rather than the selection of type or amount of polyanions, and as a result of extensive study on each element, the inventors surprisingly found that agglutination of colloidal gold may be suppressed by using a particular additive without neutralization by polyanions.

Immunochromatographic test strip for detecting object in red blood cell-containing sample and immunochromatography using the test strip

An optical measuring device includes a measuring unit (an optical head and a control unit) that irradiates a detection portion of an immunochromatographic test piece with measurement light and measures light obtained from the detection portion due to the irradiation with the measurement light, and a determination unit that performs a determination regarding the immunochromatographic test piece on the basis of a determination according to a comparison of a measurement value obtained by the measuring unit with a preset threshold value, the measuring unit performs the measurement of the light obtained from the detection portion a plurality of times, and the determination unit performs a determination regarding the immunochromatographic test piece when the determination unit determines that a measurement value in an nth measurement is equal to or greater than the threshold value and also determines that a measurement value in an (n+1)th measurement is equal to or greater than the threshold value.

Optical measuring device

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Growing community of inventors

Tokyo, Japan

Keigo Kohno