Olympus Corporation

Olympus Medical Systems Corporation

Kei Kubo

Yasushige Ishihara

Makoto Igarashi

Katsuichi Imaizumi

Satoshi Takekoshi

Hiromi Shida

Hideyuki Kugimiya

Nobuyuki Doguchi

Shunji Takei

An endoscope system includes a light source apparatus to generate an illumination light including a first light in a red to near infrared region, a second light in a green region, and a third light in a blue region, an image pickup device to pick up an image of an object and output an image pickup signal, and a processor to generate a first to third color components corresponding to the first to third lights based on an image generated according to the image pickup signal. The processor generates two of three color components that are blue, green, and red included in an observation image by using a second color component, and generates one remaining color component by using a first color component, and generates respective color components of red, green, and blue included in a white light observation image by using the first to third color components.

Endoscope system and image processing method

A video processor includes: a region extracting circuit that receives an input of a first image signal obtained by forming an image of a subject irradiated with first narrow band light including a wavelength that is minimally absorbed by blood within a green wavelength band, the image of the subject including a bleeding point, and extract a blood pool region having a blood concentration that is lower than a blood concentration of the bleeding point in a region representing the blood in the first image signal; and an image generating circuit that raises a luminance value of the blood pool region in either the first image signal or a second image signal obtained by forming an image of the subject irradiated with second narrow band light whose wavelength is shorter and which is more absorbed by the blood than the first narrow band light.

Image processing apparatus that identifiably displays bleeding point region

A living body observation system has a light source apparatus configured to generate white observation light and excitation light for exciting fluorescent medical agent, a camera unit configured to pick up an image of a subject, a switch capable of giving an instruction to switch an observation mode, and a processor. The processor generates a white observation image and a fluorescent image; judges whether or not a parameter acquired based on the fluorescent image meets a condition under which observation of fluorescence is possible, switches to a fluorescence observation mode if the condition under which observation of the fluorescence is possible is met, when an instruction is given in a normal observation mode, and switches to a predetermined observation mode different from the fluorescence observation mode if the condition under which observation of the fluorescence is possible is not met.

Living body observation system

A fluorescence observation apparatus including a light source that radiates illumination light and excitation light; a return-light-image generating portion and a fluorescence-image generating portion that generate a return-light image and a fluorescence image, respectively; a fluorescence detecting portion that detects a fluorescence region in the fluorescence image; a return-light-image adjusting portion that adjusts gradation values of the return-light image; a superimposed-image generating portion that generates a superimposed image by using the return-light image, in which the gradation values have been adjusted, and the fluorescence image; and a coefficient setting portion that sets, in the case in which the fluorescence region is detected, a degree-of-reduction of the gradation values, so that the gradation values of the return-light image are decreased as compared with the case in which the fluorescence region is not detected.

Fluorescence observation apparatus

An image processing apparatus includes an input section, a specification section, an extraction section, and a calculation section. The input section receives fluorescence image information obtained by picking up an image of fluorescence based on application of excitation light to a subject provided with a fluorescent substance with a specific effect on a living tissue and therapeutic light position image information including an application position of therapeutic light. The specification section specifies an application region of the therapeutic light. The extraction section extracts a luminance value corresponding to the application region of the therapeutic light and a luminance value corresponding to a region other than the application region of the therapeutic light. The calculation section calculates and outputs a ratio of the extracted luminance value corresponding to the application region to the luminance value corresponding to the region other than the application region.

Image processing apparatus

Provided is a fluorescence observation apparatus including: a fluorescence image acquisition section and a reference image acquisition section that acquire a fluorescence image and a reference image of a subject, respectively; a division image generation section that generates a division image by dividing an image based on the fluorescence image by an image based on the reference image; a display section that displays a corrected fluorescence image based on the division image; a correction processing section that applies correction processing to at least one of the reference image and the fluorescence image and/or to the division image prior to the generation of the division image or prior to the display of the corrected fluorescence image; an observation condition determination section that determines observation conditions of the subject; and a correction condition setting section that sets parameters regarding the correction processing according to the observation conditions.

Fluorescence generated at a lesion is distinguished from fluorescence generated at portions other than the lesion, and thus, observation is performed by using only the fluorescence generated at the lesion. Provided is a fluorescence observation apparatus including a light radiating portion that radiates excitation light onto an examination subject; a fluorescence-distribution acquiring portion that acquires an intensity distribution of fluorescence generated at the examination subject due to irradiation with the excitation light from the light radiating portion; and a non-target-region excluding portion that, in the fluorescence-intensity distribution acquired by the fluorescence-distribution acquiring portion, excludes regions in which a spectrum in a specific wavelength band has changed due to a specific biological component whose concentration in a lesion is lower than in other portions.

Apparatus, method and operating method of apparatus for excluding non-target-region of fluorescence

The invention provides a fluoroscopy apparatus including an image-capturing device that acquires a fluorescence image of a subject; a sensitivity adjusting portion that sets a sensitivity of the image-capturing device to fluorescence on the basis of a gradation value of the fluorescence image; a notifying portion that extracts a lesion part from the fluorescence image acquired by the image-capturing device with the sensitivity set by the sensitivity adjusting portion and presents it to an operator; and a display switching portion that displays the fluorescence image on a display unit when the sensitivity in the image-capturing device is equal to or less than a predetermined threshold and that presents information showing the existence of the lesion part on the notifying portion when the sensitivity is greater than the predetermined threshold.

Fluoroscopy apparatus and fluoroscopy apparatus operating method

Provided is a fluoroscopy apparatus including a light source that irradiates an observation target with reference light and excitation light; a fluorescence-image generating unit that captures fluorescence emitted from the observation target X irradiated with the excitation light to generate a fluorescence image; a reference-image generating unit that captures return light returning from the observation target irradiated with the reference light to generate a reference image; an image-combining unit that superimposes the fluorescence image on the reference image to generate a combined image; a determining unit that determines whether there is a position with a luminance at or below a predetermined threshold in the reference image; and a notifying unit that, if the determining unit determines that there is a position with a luminance at or below the predetermined threshold, provides notification thereof.

Fluoroscopy apparatus and fluoroscopy system

Provided is a fluoroscopy apparatus including a fluorescence-image generating portion that generates a fluorescence image; an identifying portion that identifies a position of a high-luminance region in the fluorescence image; a storage portion that stores the position of the high-luminance region; a detecting portion that detects an amount of change in a physical quantity, which can possibly act as a cause of changes in a property of the high-luminance region, starting from a time at which the position of the high-luminance region is identified by the identifying portion; a confidence-level calculating portion that calculates a confidence level of the property of the high-luminance region based on the detected amount of change; and a display-image generating portion that generates a display image in which the display mode at the position of the high-luminance region is set in accordance with the confidence level.

Fluoroscopy apparatus

A medical apparatus includes: a storing section in which information concerning a drug kinetics in a living body is stored in advance for each of plural kinds of fluorescent drugs; a processing section that acquires information concerning diagnosis start timing corresponding to a desired fluorescent drug based on information stored in the storing section, information concerning a target region to which the desired fluorescent drug is administered, information concerning a method of administering the desired fluorescent drug to the target region, and information indicating start of the administration of the desired fluorescent drug; and a light source control section that controls radiation of excitation light for exciting the desired fluorescent drug to a stop state until the diagnosis start timing is reached and controls, at and after the diagnosis start timing, the radiation of the excitation light to a state in which the excitation light can be radiated.

Medical apparatus

A medical apparatus includes a storing section in which information concerning a drug movement in a living body is stored for each of types of a plurality of fluorescent drugs, an arithmetic processing section that acquires, based on the information stored in the storing section, information concerning a target region to which a fluorescent drug is administered, information concerning a method of administering the fluorescent drug to the target region, and information indicating start of administration of the fluorescent drug, information concerning diagnosis start timing, an image pickup section, a position information acquiring section that acquires position information of the image pickup section, and a light source control section that stops, at least from the administration start timing to the diagnosis start timing, irradiation of excitation light and irradiates the excitation light based on the diagnosis start timing and the position information.

Medical apparatus for control of excitation light based on image sensor position and fluorescent drug information

A medical apparatus includes a storing section in which information concerning a drug movement in a living body is stored, an arithmetic processing section that acquires, based on the information stored in the storing section, information concerning a target region to which a first fluorescent drug is administered, information concerning a method of administering the first fluorescent drug, and information indicating start of administration, diagnosis end timing corresponding to the first fluorescent drug and sets, administration start timing of a second fluorescent drug, and a control section that performs control to start the administration of the second fluorescent drug when a current time reaches the administration start timing of the second fluorescent drug and, after the diagnosis end timing corresponding to the first fluorescent drug, performs control to reduce an irradiating light amount of excitation light for exciting the first fluorescent drug.

A fluorescence observation apparatus according to the present invention includes a light source section that emits excitation light for exciting a first fluorescent substance and a second fluorescent substance, a fluorescence detection section that detects first fluorescent light emitted when the first fluorescent substance is excited and second fluorescent light emitted when the second fluorescent substance is excited, a correction value calculation section that calculates a correction value for canceling a color mixture between the first fluorescent light and the second fluorescent light based on feature values corresponding to characteristics of the first fluorescent substance and the second fluorescent substance, a detected image generation section that generates a first detected image corresponding to a detection result of the first fluorescent light and a second detected image corresponding to a detection result of the second fluorescent light, and an image correction section that corrects a luminance value of the first detected image to a luminance value corresponding to intensity of the first fluorescent light and corrects a luminance value of the second detected image to a luminance value corresponding to intensity of the second fluorescent light.

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Hino, Japan

Kei Kubo