Korea Institute of Radiological & Medical Sciences

Other

Kee Ho Lee

Sung H Hong

In Seok Hong

Sang Jun Park

Eun Ju Lee

Yang Hyun Kim

Hyun Jin Shin

Jie Young Song

Hyun Jung Baek

Hee Chung Kwon

Chun Ho Kim

Sung Sub Kim

Eun Ran Park

Mi-yeun Kim

Masahide Kuroki

Melanophilin (MLPH) of the present invention is involved in differentiation into an adipocyte or fat accumulation, and accordingly, obesity can be treated or prevented by inhibiting the MLPH. Further, by measuring an expression level of the MLPH, obesity can be diagnosed and treated, and therapeutic agents for obesity and agents regulating differentiation into adipocytes can be screened.

Pharmaceutical composition for treating or preventing obesity

A method for preparing mixture powders of platycodon grandiflorus and momordica charantia includes washing at least one year-old platycodon grandiflorus, and momordica charantia wherein the platycodon grandiflorus includes stem, root, and leaf portions thereof; cutting the washed platycodon grandiflorus and momordica charantia; hot air-drying the cut platycodon grandiflorus and momordica charantia in a dryer at a temperature exceeding a boiling point of hydrogen cyanide gas to remove hydrogen cyanide therefrom; pulverizing the cut and dried platycodon grandiflorus and momordica charantia to prepare platycodon grandiflorus powders and momordica charantia powders; and mixing the platycodon grandiflorus powders and momordica charantia powders to produce the mixture powders of platycodon grandiflorus and momordica charantia.

Mixture powders of platycodon grandifloras and momordica charantia, and method for producing the powders

Provided are a compound represented by Formula I, a pharmaceutically acceptable salt thereof, or a solvate thereof; and a pharmaceutical composition for cancer treatment and a pharmaceutical composition for a radiation sensitizer for cancer treatment, each pharmaceutical composition including the compound of Formula I, the pharmaceutically acceptable salt thereof, or the solvate thereof: 

Benzothiazole derivatives and a use thereof for the treatment of cancer

Provided are an isolated protein derived from an N-terminal of HveA/HVEM and having activity of increasing the cell infectivity of herpes simplex virus (HSV) and use thereof.

Protein increasing cell infectivity of herpes simplex virus and use thereof

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Seoul, South Korea

Kee Ho Lee