Accutar Biotechnology Inc.

Sharkgulf Technology (qingdao) Co., Ltd.

Keiper Seating Mechanisms Co., Ltd.

Tiger Biotherapeutics Inc.

Ke Liu

Jie Fan

Wei He

Yimin Qian

Hui Hu

Hui Zhang

Jie Su

Bin Huang

Peng Li

Dong Liu

Robert Zhiyong Luo

Ji Liu

Tong Chen

Pin Huang

Yan Feng

Robert Luo

Junjie Wang

Xiangyan Sun

Sun Xiangyan

Shiyao Liu

An early-warning system, method, and apparatus for steering of a two-wheeled vehicle, and a corresponding two-wheeled vehicle including a display apparatus. The system includes: a first control system and a second control system both operating independently and exchanging data between each other in real time; the first control system is configured to: monitor a steering state of the two-wheeled vehicle in real time and generate steering state data; generate early-warning state data based on the steering state data; transmit at least part of the steering state data and the early-warning state data to the second control system in real time; and control corresponding components of the two-wheeled vehicle to operate according to control instructions received from the second control system and internal preset instructions; and the second control system is configured to: control a display of the display apparatus based on the steering state data and/or the early-warning information.

Early-warning system, method and device for steering of two-wheeled vehicle, and corresponding two-wheeled vehicle

The present application pertains to the technical field of vehicles, and in particular to a vehicle intelligent control system based on a dual independent control system and a corresponding vehicle. The system includes a locomotive terminal and a cloud server. The locomotive terminal includes a first control system and a second control system both being operable independently and capable of exchanging data with each other in real time. The first control system monitors an operation state of the vehicle in real time and transmits at least part of operation state data to the second control system in real time, and controls an operation of the vehicle according to an internal preset instruction and a control instruction received from the second control system. The second control system receives data transmitted by the first control system and transmits at least part of the received data to the cloud server, and receives a control instruction from the cloud server and forwards the control instruction for controlling the operation of the vehicle to the first control system. The present application improves the adaptability and stability of the system, enhances the user experience and increases the safety of the vehicle.

Double independent control unit-based intelligent vehicle control system and vehicle

Disclosed are an audio information transmission system, method, and apparatus, and a corresponding two-wheeled vehicle and helmet. The system includes a media control apparatus and an audio switching apparatus connected to the media control apparatus. The audio switching apparatus is connected to a mobile terminal and the helmet and is configured to receive first audio information transmitted by the mobile terminal and transmit same to the media control apparatus. The media control apparatus is configured to receive and mix second audio information generated by the two-wheeled vehicle with the first audio information, to generate mixed audio information. The audio switching apparatus transmits the mixed audio information to the helmet. In the present application, the audio information transmitted by the mobile terminal and information such as navigation voices, alarms emitted by the two-wheeled vehicle are mixed. The mixed audio information is transmitted to the helmet, so that the user can obtain both the audio information transmitted by the user terminal and the navigation voices transmitted by the electric vehicle, without switching between the audio information from the mobile terminal and the navigation voices emitted by the electric vehicle. The user's driving safety is improved and the user experience is enhanced.

Audio information transmission system, method, device, corresponding two wheeled vehicle, and helmet

The present disclosure relates to novel glutarimide-containing compounds with KRAS mutant form degradation activities, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of diseases and conditions.

Glutarimide-containing KRAS-mutant degrader compounds and uses thereof

The present disclosure relates to novel compounds, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of cancer and related diseases and conditions. In some embodiments, the compounds disclosed herein exhibit androgen receptor degradation activity.

Substituted quinoline-8-carbonitrile derivatives with androgen receptor degradation activity and uses thereof

The present disclosure relates to novel compounds of Formula (I) that degrade Bruton's tyrosine kinase (BTK), pharmaceutical compositions containing such compounds, and their use in prevention and treatment of conditions modulated by BTK. 

Substituted pyrrolopyrimidine and pyrazolopyrimidine as Bruton's tyrosine kinase (BTK) degraders

A computer-implemented method for predicting a conformation of a ligand docked into a protein is disclosed. According to some embodiments, the method may include determining one or more poses of the ligand in the protein, the poses being representative conformations of the ligand. The method may also include determining, using a neural network, energy scores of the poses. The method may further include determining a proper conformation for the docked ligand based on the energy scores.

Computational method for classifying and predicting ligand docking conformations

A memory module includes a pressure tongue rotatably mounted on a fixed block through a reset spring providing a first driving force for rotation of the pressure tongue. A rotating block is rotatably mounted on a slider through a torsion spring providing a second driving force for rotation of the rotating block, and the slider is slidably mounted on a guide rail. When the rotating block projects forwards under the action of the second driving force, a locking block is inserted into a locking hole, and an upper retaining surface is separated from a first lower retaining point. When the pressure tongue presses the rotating block downwards under the action of the first driving force to overcome the second driving force to force the rotating block to raise backwards, the locking block is separated from the locking hole, and the upper retaining surface is contact with the first lower retaining point.

Memory module and seat mounting structure with easy entry module

Ureas having Androgen Receptor degradation activity and uses thereof

Substituted quinoline-8-carbonitrile derivatives having androgen receptor degradation activity and uses thereof

The present disclosure relates to novel compounds, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of cancer and related diseases and conditions.

Chroman derivatives having estrogen receptor degradation activity and uses thereof

Ureas having androgen receptor degradation activity and uses thereof

The present disclosure relates to novel compounds having estrogen receptor alpha degradation activity, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of cancer and related diseases and conditions.

Compounds having estrogen receptor alpha degradation activity and uses thereof

The present disclosure relates to novel compounds, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of estrogen-related diseases and conditions.

A computer-implemented method for predicting molecule properties is disclosed. According to some embodiments, the method may include receiving an input file of a compound. The method may also include implementing a neural network to determine molecular configurations of the compound based on the input file and a plurality of molecular descriptors associated with the compound. The method may also generating, using the neural network, one or more three-dimensional (3D) models of the compound based on the determined molecular configurations of the compound. The method may also include determining, using the neural network, energy scores of the one or more 3D models when the compound is docked into a protein. The method may further include determining a property of the docked compound based on the energy scores.

Growing community of inventors

Shanghai, China

Ke Liu