The University of North Carolina at Chapel Hill

Other

Genentech, Inc.

Pharmacia & Upjohn Company

Ke Chen

Kuo-Hsiung Lee

Sheng-Chu Kuo

Richard Allen Nugent

Joseph Walter Strohbach

Valerie Ann Vaillancourt

Sajiv Krishnan Nair

John Kenneth Dickson, Jr

Jose Mendoza

Audris Huang

James A Nieman

Carl Nicholas Hodge

Sandra Staley

Robert C Kelly

Fan Yang

Jeffrey Allen Pfefferkorn

Mark Allen Mitchell

Lee Andrew Funk

Huanchen Li

Nancy Anne Wicnienski

Rebecca Merry Anderson

Bo Zhang

Meredith L Greene

Matthew Todd Reding

Priya Rani

Sridevi Ramaswamy

Ramaswamy Venkateshwaran

Richard Frederick Heier, Iii

Jose Serafin Mendoza

John K Dickson Jr

A computerized method for reducing domain noise, creating and summarizing human-written sentences into clusters for efficient tagging in natural language processing comprising: receiving a typed, handwritten or printed text; implementing an optical character recognition (OCR) process on human written text to generate a digital version of the human written text; splitting the digital version of the typed, handwritten or printed text into an array of sentences, using a sentence splitter to generate a split sentence version; determining a domain of the human written text; based on the domain, implementing a domain noise reduction process on the split sentences version; hierarchically clustering the split sentences version after the domain noise reduction process; and summarizing the clustered sentences and reducing the amount of data to be tagged.

Method and system of creating and summarizing unstructured natural language sentence clusters for efficient tagging

2-Amido-4-substituted-aryl-thiazole-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, methods of using compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions comprising compounds exhibiting ATP-utilizing enzyme inhibitory activity, are disclosed.

2-amido-thiazole-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof

2-Amido-thiazole-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof

The present invention relates to compounds, process for their synthesis, compositions and methods for the treatment and prevention of hepatitis C virus (HCV) infection. In particular, the present invention provides novel compounds, pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment or prevention of HCV infection. The present invention also provides processes and intermediates for the synthesis of these compounds.

Inhibitors of HCV NS5B polymerase

Pyrroloquinolones as antiviral agents

The present invention provides compounds of Formula I:

Method for treating tumors using 2-aryl-naphthyridin-4-ones

The present invention provides compounds of Formula I: ##STR1## wherein A and R.sub.1 -R.sub.8 are defined herein. The compounds of Formula I inhibit the polymerization of tubulin and possess antimitotic activity. The compounds of Formula I may be useful for the treatment of psoriasis, gout, papiloma, warts, and a variety of tumors.

Growing community of inventors

Chapel Hill, NC, United States of America

Ke Chen