Smithkline Beecham Corporation

Kazys A Razgaitis

John G Gleason

Paul E Bender

Nabil Hanna

Jerry Leroy Adams

Ivan Lantos

Don Edgar Griswold

Henry M Sarau

Carl D Perchonock

John F Newton

Susan C Shilcrat

A method of inhibiting the 5-lipoxygenase pathway in an animal in need thereof which comprises administering an effective, 5-lipoxygenase pathway inhibiting amount of a diaryl- substituted imidazole fused to a thiazole pyrrolidine, thiazide or piperidine ring to such animal.

Inhibition of the 5-lipoxygenase pathway

Compounds comprising pyridyl and phenyl substituted pyrrolo[1,2-a]imidazole derivatives and pyridyl and phenyl substituted imidazo[1,2-a]pyridine derivatives, pharmaceutical compositions containing said compounds, and their use as 5-lipoxygenase pathway inhibitors.

Pyrrolo(1,2-a)imidazole and imidazo(1,2-a)pyridine derivatives and their

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Rosemont, PA, United States of America

Kazys A Razgaitis