Maruha Corporation

Maruha Nichiro Seafoods, Inc.

Kazuyoshi Yoshikai

Masazumi Nishikawa

Tadakazu Tamai

Itsuki Murota

Kunio Ogasawara

The present invention provides an oral preventive or therapeutic agent for skin damage, containing diacylglyceryl ether as an active ingredient represented by the formula (I): wherein Rdenotes Caliphatic hydrocarbon group having a degree of unsaturation of between 0 and 2; Rdenotes Cacyl group having a degree of unsaturation of between 0 and 6; and Rdenotes Cacyl group having a degree of unsaturation of between 0 and 6.

Oral preventive/therapeutic agent for skin damage containing diacylglyceryl ether

The present invention relates to aliphatic compounds of the formula I, or stereoisomers thereof, or their pharmaceutically acceptable salts:wherein A represents an optionally substituted CHCH&#x2014; (wherein n denotes an integer of 4 to 22, and m represents an unsaturation number which is an integer of 0 to 7), l represents an integer of 0 to 10, s represents 0 or 1, provided that when s is 0, p+q=4 or 5, but when s is 1, p+q=3 or 4, and in each case, either p or q is an integer of 1 or more, R represents an alkyl group having 1 to 10 carbon atoms which may be straight-chain or branched-chain, and Rrepresents hydrogen or an alkyl group having 1 to 10 carbon atoms which may be straight-chain or branched-chain, and their use in suppression of platelet aggregation, in suppression of inflammation, and in prevention and treatment of circulatory diseases.

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Ibaraki, Japan

Kazuyoshi Yoshikai