Fuso Pharmaceutical Industries, Ltd.

Kinki University

Kazuya Murata

Atsufumi Kawabata

Hiroyuki Nishikawa

Fumiko Sekiguchi

Hideaki Matsuda

The present invention provides a T-type calcium channel inhibitor which is a compound represented by formula (1), a pharmaceutically acceptable salt of this compound or a solvate of this compound. The present invention also provides: this T-type calcium channel inhibitor; a pharmaceutical product containing this T-type calcium channel inhibitor; and a therapeutic agent or prophylactic agent for diseases, the effective action of which is a T-type calcium channel inhibitory action. (In formula (1), each of Rand Rindependently represents H, &#x2014;OH or &#x2014;ORwherein Rrepresents a Calkyl group; each of Rand Rindependently represents H, &#x2014;OH or &#x2014;OR, wherein Rrepresents a Calkyl group; and each of Rand Rindependently represents H, a halogen atom, a Calkyl group, a Calkenyl group, a Calkynyl group, a phenyl group (which may be substituted by a Calkoxy group or a halogen atom), a &#x2014;Calkyl-phenyl group (which may be substituted by a Calkyloxy group or a halogen atom) or a Cprenyl group.) 

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Higashiosaka, Japan

Kazuya Murata