Ajinomoto Co., Ltd.

Kazuya Kondo

Yusuke Takahashi

Takahiro Asano

Akihiro Watanabe

Shintaro Iwatani

Wataru Hibino

Kohei Ishikawa

Satoshi Okutani

Masayuki Araki

Yuriko Murakoshi

Fumito Ohnishi

A method for producing a carboxylic acid by a fermentation process which comprises culturing a methanol-assimilating bacterium capable of producing the carboxylic acid in a liquid medium containing methanol and a counter ion to produce and accumulate the carboxylic acid in the medium, further comprising the feeding of a substance comprising methanol and a counter ion to the medium by fed-batch culturing to maintain the total ionic strength within the fermentation medium at or below a certain level.

Method for producing carboxylic acid using methanol-assimilating bacterium

A method is described for producing an L-amino acid or a nucleic acid by culturing a microorganism having an ability to produce the L-amino acid or nucleic acid in a liquid medium in a fermentation tank containing a stirring impeller, and optionally adding seed crystals to the medium as required to produce and accumulate crystals of the L-amino acid or nucleic acid in the medium, and collecting crystals of the L-amino acid or nucleic acid from the culture. The power density of the stirring impeller is controlled to be 2.4 kW/mor lower after either precipitation of the crystals or addition of the seed crystals.

Method for producing an L-amino acid or a nucleic acid

Growing community of inventors

Kawasaki, Japan

Kazuya Kondo