Osaka University

Hamamatsu University School of Medicine

National University Corporation Hamamatsu University School of Medicine

Kazuya Hokamura

Kazuo Umemura

Takashi Ooshima

Ryota Nomura

Koichiro Wada

Kazuhiko Nakano

Disclosed is the construction of a system capable of quickly and easily identifying patients having a risk for worsening inflammatory digestive tract disease by identifying a causal factor for the worsening of the inflammatory digestive tract disease. Specifically disclosed is a method for detecting oral bacteria that cause worsening of inflammatory digestive tract disease and/or a screening that targets high risk for worsening of inflammatory digestive tract disease and/or determining the risk for worsening of the inflammatory digestive tract disease by PA not being detected and/or CBP being detected, inclusive of the detection of PA, which is an oral bacteria protein antigen, and/or CBP, which is collagen binding protein, in samples. Also disclosed are a detection reagent and kit used for this method.

Production of enteritis evoking causal factor by highly pathogenic oral bacteria and high sensitivity detection method therefor

Growing community of inventors

Hamamatsu, Japan

Kazuya Hokamura