Takasago International Corporation

Toyota Jidosha Kabushiki Kaisha

Osaka University

Kazushi Mashima

Hidenori Kumobayashi

Noboru Sayo

Hidemasa Takaya

Susumu Akutagawa

Kazuhiko Matsumura

Takanao Taketomi

Takashi Ohshima

Takanori Iwasaki

Kenya Ishida

Hirohito Hirata

Hideki Nara

Yoshimasa Matsushima

Daiki Kato

Kyoko Tamao

Hironori Maeda

Kiyoto Hori

Takuto Nagano

Tetsuo Ota

Tsuneaki Yamagata

Koji Ohno

Akihiro Yagyu

Haruki Nagae

Takahiro Hirai

Shusei Soma

Shinya Akebi

Shoko Akiyama

Masato Ohashi

Shoji Hida

Kenta Yamaji

Atsuhiro Iimuro

Yusuke Kita

A method for converting an N,N-dialkylamide compound into an ester compound includes using a fourth period transition metal complex as a catalyst. The fourth period transition metal complex is obtained by a reaction of a precursor having a fourth period transition metal with a nitrogen-containing compound or a phosphorus-containing compound.

Method for converting N,N-dialkylamide compound into ester compound using complex of fourth-period transition metal as catalyst

Disclosed is a method for producing an optically active 2-arylpiperidinium salt, comprising asymmetrically hydrogenating a pyridinium salt in the presence of an iridium complex and hydrogen, the 2-arylpiperidinium salt being represented by the following general formula (1):  

Method for producing optically active 2-arylpiperidinium salt

Disclosed is a selective ester production process of an alcoholic hydroxyl group, which proceeds under chemically mild conditions, while having adequate environmental suitability, operability and economical efficiency. Specifically disclosed is a process for producing an ester compound, which is characterized in that an alcohol and a carboxylic acid ester compound are reacted in the presence of a compound containing zinc element, thereby selectively acylating a hydroxyl group of the alcohol.

Acylation reaction of hydroxyl group

A multiple-metal complex-containing compound in accordance with an embodiment has a plurality of metal complexes in each of which a ligand is coordinated to one metal atom or a plurality of metal atoms of the same kind. The plurality of metal complexes are bound to each other via a polydentate ligand that substitutes partially the ligands of the two or more metal complexes, and have 2 to 1000 metal atoms.

Multiple-metal complex-containing compound and metal complex, and manufacture methods therefor, and exhaust gas purification catalyst manufacture method using the same

The invention relates to a method for producing an azoline compound represented by the general formula (3): wherein Rrepresents an optionally substituted hydrocarbon group, an optionally substituted alkoxy group, an optionally substituted alkoxycarbonyl group, a halogen atom, a substituted amino group, a substituted carbamoyl group or an optionally substituted heterocyclic group; R, R, Rand Rmay be the same or different and each represents a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted alkoxy group, an optionally substituted alkoxycarbonyl group, a halogen atom, a substituted amino group, a substituted carbamoyl group or an optionally substituted heterocyclic group; two arbitrary groups selected from R, R, Rand Rmay bond to each other to form a ring; and Zrepresents an oxygen atom, a sulfur atom or a selenium atom;comprising reacting a carboxylic acid or a carboxylic acid derivative represented by the general formula (1):RCOR&#x2003;&#x2003;(1)wherein Ris as defined above; Rrepresents a hydrogen atom, an optionally substituted alkyl group or an optionally substituted aryl group; and Rand Rmay bond to each other to form a ring;with an aminochalcogenide represented by the general formula (2): wherein R, R, R, Rand Zare as defined above;in the presence of a compound containing a group 12 metal element in the periodic table.

Condensation reaction by metal catalyst

The present invention has as its object to provide an iridium complex represented by the general formula:[(I r H LL)(&#x3bc;&#x2212;X)(&#x3bc;&#x2212;X)(&#x3bc;&#x2212;X)]X&#x2003;&#x2003;(1)(wherein Land Lmay be the same or different and each represent a monodendate neutral ligand, or each cooperate with the other to form a bidendate neutral ligand; X, Xand Xmay be the same or different, and each represent a halogen atom; and Xis a counter-anion). Also, the present invention provides a novel catalyst which can achieve excellent performance as a catalyst for asymmetric synthesis, especially asymmetric hydrogenation, in terms of chemical selectivity, enantioselectivity and catalytic activity, and the like.

Iridium complexes

A ligand represented by the formula (1):RRN-Q-X-Q-NRR&#x2003;&#x2003;(1)wherein R, R, Rand Rare each the same or different and represent a group represented by the formula (2): wherein Qis an optionally substituted alkylene group, an optionally substituted cycloalkylene group, an optionally substituted arylene group, or an optionally substituted divalent heterocyclic group, Ris an optionally substituted alkyl group, an optionally substituted aryl group or an optionally substituted heterocyclic group and Ris a substituent which may coordinate or bind to a metal atom, or Rand R, taken together, may form a ring, Qand Qare each the same or different and represent an optionally substituted alkylene group or a single bond, and X is a divalent spacer.

Ligands and complex compounds containing the same

Disclosed is a ruthenium-phosphine complex represented by formula (I):

Process for preparing ruthenium-phosphine complex

An iridium-optically active phosphine complex represented by formula (I):

Iridium-optically active phosphine complex and process for producing

A ruthenium-phosphine complex represented by formula (I)

Ruthenium-phoshine complex

Growing community of inventors

Ikeda, Japan

Kazushi Mashima