Kumiai Chemical Industry Co., Ltd.

Toyo Jozo Kabushiki Kaisha

Kumiai Kagaku Kogyo Kabushiki Kaisha

Kazuo Nishio

Isao Chiyomaru

Noriyasu Takayanagi

Kazuko Yamamoto

Katsuo Anma

Hiroshi Ohno

Norimichi Muramatsu

Seigo Kawada

Shigeru Tsuchiya

Yoshitaka Suda

Nobuya Ohta

Compounds of the formula wherein R is ##STR1## in which R.sub.1, R.sub.2 and R.sub.3 are the same or different and are selected from the group consisting of hydrogen, chlorine, bromine, lower alkyl, lower alkoxy and naphthyl, provided that when R.sub.1 is lower alkyl, R.sub.2 and R.sub.3 are hydrogen, chlorine, bromine or lower alkoxy, or a pharmaceutically acceptable salt thereof, have anti-carrageenin edema activity, and are useful as anti-inflammatory agents and immuno modulators. They are produced by reacting an amide of the formula ##STR2## wherein R has the same meanings hereinabove, with N,N'-ethylene thiourea.

2,3-di-substituted-5,6-dihydroimidazo [2,1-b] thiazole, its salts,

Compounds of the formula ##STR1## wherein R is ##STR2## in which R.sub.1, R.sub.2 and R.sub.3 are the same or different and are selected from the group consisting of hydrogen, chlorine, bromine, lower alkyl, lower alkoxy and naphthyl, provided that when R.sub.1 is lower alkyl, R.sub.2 and R.sub.3 are hydrogen, chlorine, bromine or lower alkoxy, or a pharmaceutically acceptable salt thereof, have anti-carrageenin edema activity, and are useful as anti-inflammatory agents and immuno modulators. They are produced by reacting an amide of the formula ##STR3## wherein R has the same meanings hereinabove, with N,N'-ethylene thiourea.

2,-3-Di-substituted-5,6-dihydroimidazo [2,1-b] thiazole, its salts,

The present invention relates to a compound having the following general formula (I): ##STR1## wherein X stands for a halogen atom or a methyl radical; and R stands for an alkyl or alkoxy radical containing 3 to 6 carbon atoms provided that R represents an alkyl radical containing 3 to 6 carbon atoms when X is a methyl radical, a process for the production thereof, an agricultural composition containing the said compound as an effective component, and a method for preventing and healing the diseases of the plant and in soil using the said compound.

Fungicidal and germicidal benzanilides

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Saitama, Japan

Kazuo Nishio