The University of Tokyo

Tanita Corporation

Tokyo University of Agriculture and Technology

Teijin Pharma Limited

Media Kobo, Inc.

Kyoto University

Kazuo Nagasawa

Yuichi Hashimoto

Yutaka Abe

Motonari Uesugi

Haruka Nakamura

Yoshihiro Ozeki

Hayato Nakagawa

Nobuhiro Sasaki

Yasushi Takemoto

Yuki Matsuba

Fumihiro Kawagoe

Kazuma Ohashi

Yuko Kato

Masayuki Tera

Atsushi Kittaka

Yuichi Takahama

Mamoru Shinozaki

Hachiro Tubaki

Yasao Mikami

Risa Asano

Mizuki Watanabe

Provided are vitamin Dderivatives of formula (I), pharmaceutical compositions thereof, and pharmaceutical or medical uses thereof for treating metabolic disease, a liver disease, obesity, diabetes, cardiovascular disease, or cancer in a patient in need thereof.

VDR-silent vitamin D derivative as inhibitors of SREBP and pharmaceutical use thereof

A display request including designation related to a display state of a stereoscopic shape in a three-dimensional space is transmitted from a receiving apparatusto a transmitting apparatus, and the transmitting apparatusextracts point cloud data of a part corresponding to the display request from among the point cloud data stored in a point cloud data storage unitin response to the display request and transmits the extracted point cloud data to the receiving apparatus. Accordingly, only the point cloud data of the part which is necessary for the display state of the stereoscopic shape which is actually displayed in the three-dimensional space by the receiving apparatusis transmitted, and thus it is possible to transmit only the point cloud data necessary for display within a practically acceptable short time on a communication networkeven though the entire data amount of the point cloud data stored in the point cloud data storage unitis huge.

Point cloud data communication system, point cloud data transmitting apparatus, and point cloud data transmission method

An object of the present invention is to provide a sugar donating reagent comprising a sugar donor compound other than a sugar nucleotide and an enzyme capable of catalyzing a glycosyl transfer reaction using a sugar donor compound other than a sugar nucleotide. The present invention provides the following: a sugar donating reagent containing a compound of formula (A): wherein Ris independently selected from hydrogen, or Calkyl, Calkenyl, and Calkynyl in which each of the groups is unsubstituted or substituted with one or more groups selected from OH, F, Cl, Br, I, CN, NO, and SO, n is 0, 1, 2, 3, 4 or 5, m is 0 or 1, and X represents a monosaccharide bound via a &#x3b2; bond on its anomeric carbon; a glycosyltransferase capable of catalyzing a glycosyl transfer reaction using the sugar donor; and a glycosyltransferase gene comprising DNA encoding the glycosyltransferase.

Glycosyltransferase, novel glycosyltransferase gene, and novel sugar donor compound

Compounds expressed by the following formula (1) or pharmaceutically permissible solvate thereof which is effective for treating Paget's disease of bone, hypercalcemia or osteoporosis.  In the formula, Ris a C-Calkyl group, or a C-Caralkyl group whose aromatic ring is optionally substituted with a C-Calkyl group, a C-Calkoxyl group, a hydroxyl group, a halogen atom or a trifluoromethyl group; and Ris a C-Calkyl group, or a C-Caralkyl group whose aromatic ring is optionally substituted with a C-Calkyl group, a C-Calkoxyl group, a hydroxyl group, a halogen atom or a trifluoromethyl group.

[object Object]

Driving wheels for auxiliary rotary wheels are provided at the forward corners of a sweeper in a spaced relationship from driving wheels for a main rotary brush to provide a long wheel base.

Hand sweeper for carpets

Growing community of inventors

Tokyo, Japan

Kazuo Nagasawa