Hitachi, Ltd.

The University of Texas System

Other

Hokkaido University

Director General of National Institute of Radiological Sciences

Kazuo Hiramoto

Hiroshi Akiyama

Koji Matsuda

Junichi Hirota

Masatsugu Nishi

Masumi Umezawa

Masahiro Tadokoro

Alfred Smith

Tetsuro Norimine

Hisataka Fujimaki

Masaki Yanagisawa

Yoshihiko Nagamine

Wayne David Newhauser

Yusuke Vincent Fujii

Kenji Miyata

Kikuo Umegaki

Yoshihiro Michiguchi

Fumiaki Noda

Hiroshi Kubo

Fuminobu Takahashi

Hideaki Nishiuchi

Takayoshi Seki

Kazuyoshi Saito

Shinichi Shimizu

Takamitsu Hae

Yoshihisa Iwashita

Kazuyoshi Saitou

Takahiro Yamada

Kensuke Amemiya

Motoo Aoyama

Naoki Miyamoto

Masahiro Yoshida

Takamichi Aoki

Shinichiro Fujitaka

Renzo Takeda

Hiroyuki Watanabe

Akira Noda

Kunio Moriyama

Toru Umekawa

Hiroki Shirato

Taeko Matsuura

Yukiharu Ohga

Masaharu Sakagami

Rintaro Fujimoto

Seishin Takao

Kazuyoshi Miki

Hideaki Nihongi

Hiroaki Sakurabata

Shigemitsu Hara

Shinji Sonoda

Rika Baba

Motomasa Fuse

Masanobu Tanaka

Yusuke Fujii

Toshie Sasaki

Akiko Kakiuchi, Legal Representative

Akifumi Itano

Makoto Inoue

Tetsuo Norimine

Koji Mtsuda

Masahide Nakamura

Koji c/o Hitachi Ltd Intellect Prop Matsuda

Hideaki Nihonghi

In a circular accelerator that applies a radiofrequency wave in a main magnetic field to accelerate charged particle beam while increasing an orbit radius, another radiofrequency wave with a frequency different from the radiofrequency wave used for acceleration is applied to the charged particle beam in order to extract the charged particle beam. Thereby, in the circular accelerator that accelerates charged particle beam while increasing an orbit radius by applying a radiofrequency wave in a main magnetic field, the high precision control on extraction of the charged particle beam from the circular accelerator is achieved.

Circular accelerator, particle therapy system with circular accelerator, and method of operating circular accelerator

First ions and second ions that are heavier than first ions are generated in an ion source. One kind of ions of the first ions and second ions is injected into an accelerator by action of a switching magnet and accelerated in the accelerator. An ion beam including the one kind of ions is extracted from the accelerator to a beam transport system and a tumor volume of a patient is irradiated with the ion beam from an irradiation nozzle. In the irradiation of the ion beam, a tumor volume depth and the largest underwater range of each ion species are compared, and an ion species in which the tumor volume depth becomes the longest underwater range or lower is injected into the accelerator, and accelerated by the accelerator. The tumor volume is irradiated with the ion species.

Charged particle beam system

A radiotherapy system acquires an image which is necessary for positioning of a patient for radiation treatment and enables grasping of a positional relationship of a target in a treatment radiation irradiated state, a radiation passing area and a critical organ. An X-ray imaging device is attached to the rotatable support device and configured to apply X-rays to the subject from plural directions while rotating around the subject to perform X-ray imaging. A target recognizing device recognizes a three-dimensional position of the target in the subject from X-ray images acquired by the X-ray imaging device; and CT image generating devices are configured to select, from the X-ray images acquired by the X-ray imaging device, the images in which the position of the target recognized by the recognizing device satisfies the treatment radiation irradiation condition for the motion tracking treatment to perform image reconstruction and generate a cone beam CT image.

Radiotherapy system

A charged particle beam reduces treatment time in the uniform scanning or in the conformal layer stacking irradiation. In the uniform scanning, an optimum charged particle beam scan path for uniformly irradiating a collimator aperture area is calculated. In the conformal layer stacking irradiation, an optimum charged particle beam scan path for uniformly irradiating a multi-leaf collimator aperture area of each layer for each of the layers obtained by partitioning the target volume is calculated. Alternatively, a minimum irradiation field size that covers the multi-leaf collimator aperture area of each layer is calculated, and a scan path corresponding to the irradiation field size, prestored in a memory of a particle therapy control apparatus, is selected. The charged particle beam scan path is optimally changed in the lateral directions in conformity with the collimator aperture area in the uniform scanning or in each layer in the conformal layer stacking irradiation.

Treatment planning apparatus and particle therapy system

Disclosed herein are provided an arrangement of devices suitable to downsize a synchrotron, a synchrotron using such an arrangement, and a particle therapy system using the synchrotron. In the synchrotron, a plurality of deflection magnets and a single defocusing quadrupole magnet are arranged between a first extraction deflector and a second extraction deflector. The defocusing quadrupole magnet is arranged between deflection magnets among the plurality of deflection magnets, a focusing quadrupole magnet is arranged on the side of an inlet of the first extraction deflector, and a focusing quadrupole magnet is arranged on the side of an outlet of the second extraction deflector.

Synchrotron and particle therapy system using the same

A charged particle beam irradiation system includes a synchrotron which accelerates an ion beam, an irradiation apparatus for irradiating an object with the ion beam introduced from the synchrotron, detection means for measuring an amount of accumulated charge of the ion beam that orbits in the synchrotron immediately before an extraction control period in an operating cycle of the synchrotron, and beam extraction control means for controlling extraction of the ion beam based on the measurement result of the accumulated beam charge amount so that extraction of a total amount of the ion beam is to be completed with an expiration of an extraction control time, the extraction control time representing a length of the extraction control period of the synchrotron and being set in advance.

Charged particle beam irradiation system and charged particle beam extraction method

In a charged particle irradiation system, forming a uniform dose distribution is required by irradiating a moving irradiation object through beam scanning and energy stacking. The charged particle irradiation system includes an ion beam generatorfrom which an ion beam is extracted with a target beam current value thereof set; an irradiation nozzlehaving scanning magnetsand an energy filter, the irradiation nozzlefor irradiating an irradiation object with the ion beam; and an irradiation object monitoring unitfor measuring a position of the irradiation object and outputting signals that vary with time according to displacement of the irradiation object. The charged particle irradiation system determines extraction timing of the ion beam based on the signal outputted from the irradiation object monitoring unitand sequentially changes energies of the ion beam to thereby perform a repainting irradiation with each of the energies.

Charged particle irradiation system and irradiation planning equipment

A charged particle irradiation system that positions the beam at a target position to avoid irradiation of normal tissue includes an acceleration systemfor extracting a charged particle beam, scanning magnetsand, and charged particle beam position monitorsand. On the basis of signals received from the charged particle beam position monitorsand, the control unitcalculates a beam position at a target position and then controls the scanning magnetsandso that the charged particle beam is moved to a desired irradiation position at the target position. The control unitcorrects the value of an excitation current applied to each of the scanning magnetsandon a specified cycle basis on the basis of information about the position and the angle of the charged particle beam.

Charged particle irradiation system

A charged particle beam irradiation system and a charged particle beam extraction method which can prevent erroneous irradiation of a charged particle beam in the direction of advance of the charged particle beam. The system and method are featured in stopping supply of an ion beam to one or more of a plurality of angle zones in each of which a target dose is attained, the angle zones being formed by dividing an RMW in a rotating direction thereof, and in allowing the supply of the ion beam to one or more other angle zones in each of which a target dose is not yet attained. The invention can easily adjust beam doses at various positions in an affected part of the patient body in the direction of advance of the ion beam, and can greatly reduce the probability of erroneous irradiation that the beam dose becomes excessive or deficient at the various positions within the affected part of the patient body in the direction of advance of the ion beam.

A charged particle beam extraction system and method capable of shortening the irradiation time and increasing the number of patients treatable per unit time. The charged particle beam extraction system comprises a synchrotron for cyclically performing patterned operation including four steps of introducing, accelerating, extracting and decelerating an ion beam, an on/off switch for opening or closing connection between an RF knockout electrode and an RF power supply for applying RF power to the RF knockout electrode, and a timing controller for controlling on/off-timing of the on/off switch such that when extraction of the ion beam is stopped at least once during the extraction step of the synchrotron, an amount of the ion beam extracted from the synchrotron in one cycle is held substantially at a setting value.

Charged particle beam extraction system and method

To ensure irradiation accuracy and safety, even when an irradiation device employing a different irradiation method is used, disclosed is herein a charged particle beam irradiation apparatus that irradiates an irradiation target with charged particle beams includes:

Particle beam irradiation apparatus and particle beam irradiation method

The invention is intended to increase the number of patients treatable using one wheel having a thickness varied in the rotating direction to change energy of an ion beam passing the wheel. Ion beam delivery equipment for irradiating an ion beam to a patient for treatment comprises a beam generator for producing and accelerating the ion beam, an beam delivery nozzle including a range modulation wheel which has a predetermined thickness distribution in the rotating direction and is rotated on a travel passage of the ion beam generated from the beam generator to control a range of the ion beam, and an irradiation controller for controlling the beam producing and accelerating operation of the beam generator in accordance with the phase of rotation of the range modulation wheel.

Ion beam delivery equipment and an ion beam delivery method

Ion beam delivery equipment and ion beam delivery method

A ridge filter or a range modulation wheel (RMW) is formed to have a shape corresponding to an affected part in the patient body. A plurality of spread-out Bragg peaks with the same dose or different doses are formed in the affected part by executing beam-on/off control of the RMW, beam current control with rotation of the RMW, intensity modulation control, or scanning irradiation. As an alternative, a spread-out Bragg peak containing a portion with a different dose is formed. A treatment time is cut.

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Hitachiohta, Japan

Kazuo Hiramoto