Kyowa Hakko Kogyo Co., Ltd.

Hitachi, Ltd.

Kyowa Medex Co., Ltd.

Digital Vision Laboraties Corporation

Kazuo Aisaka

Takayuki Uwajima

Osamu Terada

Katsuhiko Ando

Keiko Ochiai

Keiko Suzuki

Ryoichi Katsumata

Yoshiaki Shimizu

Toru Mizukami

Chiaki Saitoh

Akira Mihara

Hiroko Akita

Toshiaki Nagai

Hideyo Kumazawa

Yutaka Saitoh

Soshiro Kuzunuki

Yasushi Fukunaga

Hiroshi Shojima

Keisuke Toyama

Toshimi Yokota

Masaki Miura

Toshifumi Arai

Ryuichi Suzuki

Keiko Gunji

Satoshi Misaka

Youichi Uosaki

Kozo Ouchi

Akihide Hashizume

Takakazu Huno

Tooru Numata

Sakae Tazoe

Hideki Sakao

Toshiko Aisaka, Legal Representative

Kazuko Terada

A reagent measuring a glycated protein, comprising a protease and a protein of any one of [1] to [4] below:

Fructosyl peptide oxidase

The invention is directed to a protein comprising the amino acid sequence represented by SEQ ID NO: 1; a protein comprising an amino acid sequence with one to ten amino acid deletions, substitutions, or additions in the amino acid sequence represented by SEQ ID NO: 1, and having fructosyl peptide oxidase activity; a protein comprising an amino acid sequence having 99% or higher homology to the amino acid sequence represented by SEQ ID NO: 1, and having fructosyl peptide oxidase activity; and a protein having fructosyl peptide oxidase activity, which is encoded by an expression plasmid harbored by theXL1-Blue MRF' strain deposited under Accession No. FERM BP-11026; as well as uses of such proteins.

To assure the multiprocessing performance of CPU on a microprocessor, the invention provides a method of memory mapping for multiple concurrent processes, thus minimizing cache thrashing. An OS maintains a management (mapping) table for controlling the cache occupancy status. When a process is activated, the OS receives from the process the positional information for a specific part (principal part) to be executed most frequently in the process and coordinates addressing of a storage area where the process is loaded by referring to the management table, ensuring that the cache address assigned for the principal part of the process differs from that for any other existing process. Taking cache memory capacity, configuration scheme, and process execution priority into account when executing the above coordination, a computer system is designed such that a highest priority process can have a first priority in using the cache.

Cache memory allocation method

On the occasion of returning an error code to an application program to be executed under different execution environments of a computing system, it is requested to fully utilize a system of the existing instruction set to improve the ROM efficiency in the implementation of its common code and to eliminate useless insertion of instruction. For this purpose, in the present invention, a common error code to be returned, from the program to be used to be independent on different OS, to the execution program corresponding to the application program is determined as a value in the range of numerical value to be set with the instruction set of CPU and the defined instruction to load immediate value and thereby the common error code is held within the instruction code of the instruction to load immediate value. Particularly, a value of common error code is determined within the range where the MSB of the setting part of the instruction to load immediate value becomes zero (0).

Computing system construction method under execution environment to be dependent on OS

CHOLESTEROL DEHYDROGENASE, COPROSTAN-3-ONE DEHYDROGENASE AND 4-CHOLESTEN-3-ONE DEHYDROGENASE, COMPOSITIONS CONTAINING THE DEHYDROGENASES, AND METHOD FOR REDUCING AMOUNT OF CHOLESTEROL USING THE COMPOSITIONS

An enzymatic process is presented for reducing the cholesterol level of foods and feeds by converting the cholesterol therein to coprostanol which has a very low intestinal tract absorbability. Cholesterol in meat, egg, milk, seafood and cooked processed foods containing the same, or feeds for animals, poultry, and pisiculture can be reduced by the sequential action of three enzymes isolated from a eubacterium: cholesterol dehydrogenase, 4-cholesten-3-one dehydrogenase and coprostan-3-one dehydrogenase.

Process for producing a cholesterol-reduced substance

Method for quantitative determination of 1,5-anhydroglucitol

As a public key, a character string which can be easily reasoned by a person, e.g., a character string obtained by adding a specific character string, e.g., '?', of which code is an odd number to the end of a name, is used. A signature given to a document to be sent is encrypted by using a secret key generated from the public key, and the encrypted signature is sent together with a plaintext document. On the reception side, the encrypted signature is decrypted by using a public key obtained by adding a character string, '?' in this case, whose code is an odd number to the end of the name of the sender. The decrypted signature is compared with a signature included in the plaintext document, so that authentication can be performed. Since the public key need not be stored in an electronic dictionary file or the like, illegal authentication is not easily established by falsifying the public key in the electronic dictionary file.

Electronic authentication system

Process for producing disaccharides and novel disaccharides

An information processing system which comprises an integral input and display unit comprising a display which enables an object to be selectively displayed at one of a plurality of positions in a display area and a tablet having an input face overlaid on a display face of the display, the input and display face being disposed substantially horizontally, and a display whose display face is disposed substantially uprightly, wherein when an object is presented to a user in the display area of the display, a display position of the object is determined in response to at least one of a state of the user, a state of the input and display face, and a display state of the display, thereby enabling the object to be displayed at an easy-to-use position relative to the user's position.

Information processing system

Disclosed is an image display system having a plurality of CRT display screens. The system is of the type in which a number of images of specific portions of a patient having a specific ID code are selected from among a multitude of X-ray image taken by a plurality of shooting methods, and when the regions of interest are specified, a plurality of appropriate images are further selected using the previously stored aptitude values for the regions and shooting methods and displayed on said plurality of CRT display screens. In order that the segments to be inspected can be pointed to on the screen on which the image of the patient is displayed, a memory is provided which is adapted to previously store codes corresponding to the specific image of the patient and to specify the respective regions of the image in such a manner that they correspond to the pixel positions of the image.

Image display system and data input apparatus used therein

Neuraminidase is produced by culturing a neuraminidase producing microorganism belonging to the genus Micromonospora. The neuraminidase is useful for the quantitative determination of a sialic acid-containing substance in a sample.

Process for producing neuraminidase

The present invention provides a process for producing N-acetylneuraminate lyase using a microorganism constructed by recombinant DNA techniques.

Process for producing N-acetylneuraminate lyase

Glutathione peroxidase is produced by fermentation of a microorganism of the genus Mucor. This peroxidase may be used for the determination of lipid peroxide.

Glutathione peroxidase, process for production thereof, method and

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Tokyo, Japan

Kazuo Aisaka