Otsuka Pharmaceutical Company, Limited

Otsuka Electronics Co., Ltd.

Kazunori Tsutsui

Masaaki Mori

Yasuhiro Kubo

Katsuhiro Morisawa

Yasushi Zasu

Tamotsu Hamao

Eiji Ikegami

Takashi Maruyama

Tsutomu Mizuguchi

Koichi Oka

Mitsunao Sekiwa

Takashi Fujimoto

Akira Kawaguchi

Motonobu Akagi

Michio Tsujio

Atsushi Toyoshima

Masayoshi Funato

Tetsuo Hamada

The present invention provides an electrophoretic mobility measuring apparatus capable of conducting measurement with high sensitivity with optical attenuation reduced by incidence of light through the electrode face. This apparatus comprises a transparent electrodeforming a part of a cell wall of a cellcapable of confining a sample, and the other electrodeopposite to the transparent electrode. A voltage is applied across these electrodes, and light is incident upon the inside of the cellthrough the transparent electrode. The scattering light which scatters from a sample S at a predetermined angle &#x3b8; with respect to the incident angle, is received through the transparent electrode. The Doppler displacement is then measured based on the difference in frequency between the incident light and the outgoing light. The direction of the scattering vector which is the vector difference between incident and outgoing vectors, is substantially identical with that of the normal line h of the transparent electrode face.

Electrophoretic mobility measuring apparatus

A photon correlator comprises a plurality of sampling gateswhich are open during different periods of time; a plurality of memorieseach provided corresponding to each of the plurality of sampling gatesfor storing data corresponding to the number of photons; and a data processing control section for reading out the data stored in the memories, and performing a correlation calculation by means of software. The mechanism of the hardware comprising the sampling gatesand memoriesenables high-speed writing of data in the memories and real-time read out of the data. In addition, the software performs correlation calculations in parallel with the above processing. Accordingly, the particle sizes and diffusion coefficient of particles in a fluid can be obtained at high speed under various conditions.

Photon correlator

The constitution of a probe for measuring light scattering according to this invention is as follows: a light input optical fiber and a scattered light measuring optical fiber for collecting and transmitting scattered light are inserted into a main body of the probe ; the optical fiber is passed through a hole provided in the probe for measuring light scattering to extend outward; an end portion of each of the optical fibers is covered with a ferrule or ; an end of each of the ferrules is cut into the shape of a truncated cone such that a part of or the entire end face of the optical fiber or remains; and the ferrules are held by a support body and the like in such a manner that the end faces of the optical fibers are disposed to be adjacent to each other at a predetermined angle with a predetermined distance in between. Accordingly, the end portions of the optical fibers can be reinforced and protected by the ferrules even when they have poor strength. In addition, cutting the ends of the ferrules into the shape of a truncated cone allows the distance between the end faces of the optical fibers to be reduced.

Light scattering measuring probe

The present invention relates to a light scattering intensity measuring apparatus capable of measuring, as a function of the scattering angle, the intensity of the light scattered from a sample. This apparatus comprises an ellipsoidal mirror for reflecting and condensing the scattered light from a sample ; an image-forming lens disposed at the condensing point of light reflected by the ellipsoidal mirror for forming, on a camera face, the image formed on the surface of the reflection mirror ; and a camera for recording the image formed by the image-forming lens . The scattered light in a wide angle range can be detected in a very short period of time (FIG. ).

Apparatus for measuring characteristics of optical angle

A test gas sample containing carbon dioxide CO as a component gas is introduced into a cell, then the absorbance of light transmitted therethrough at a wavelength suitable for the component gas CO is determined, and the concentration of the component gas is determined on the basis of a calibration curve prepared through measurement on test gas samples each containing the component gas in a known concentration. Further, the concentration of water vapor contained in the test gas sample is measured, and the concentration of the component gas in the test gas sample is corrected in accordance with the measured water vapor concentration on the basis of a correction curve prepared through measurement on the test gas samples each containing water vapor in a known concentration (FIG. 4). With the spectrometry, the concentration ratio of the component gas can precisely be determined and corrected by measuring the moisture content in the test gas sample.

Stable isotope measurement method and apparatus by spectroscopy

A test gas sample containing carbon dioxide CO as a component gas is introduced into a cell, then the absorbance of light transmitted therethrough at a wavelength suitable for the component gas CO is determined, and the concentration of the component gas is determined on the basis of a calibration curve prepared through measurement on test gas samples each containing the component gas in a known concentration. Further, the concentration of water vapor contained in the test gas sample is measured, and the concentration of the component gas in the test gas sample is corrected in accordance with the measured water vapor concentration on the basis of a correction curve prepared through measurement on the test gas samples each containing water vapor in a known concentration (FIG. ). With the spectrometry, the concentration ratio of the component gas can precisely be determined and corrected by measuring the moisture content in the test gas sample.

A correction curve (FIG.,) is prepared by plotting,CO,concentrations and,CO,/,CO,concentration ratios which are determined on the basis of a calibration curve and,CO,and,CO,absorbances of gaseous samples having the same,CO,/,CO,concentration ratio but known different,CO,concentrations. A gaseous test sample containing,CO,and,CO,as component gases is introduced into a cell, and spectrometrically measured. A,CO,concentration of the gaseous test sample is determined by way of the spectrometric measurement. A concentration ratio correction value is obtained on the basis of the correction curve and the,CO,concentration of the gaseous test sample thus determined. A measured,CO,/,CO,concentration ratio is divided by the concentration ratio correction value thus obtained for correction of the,CO,/,CO,concentration ratio. Thus, the measurement accuracy of the concentration ratios of the component gases can be improved.

Growing community of inventors

Osaka, Japan

Kazunori Tsutsui