Yamanouchi Pharmaceutical Company Ltd.

Kazuhito Tanabe

Makoto Takeuchi

Atsushi Ichikawa

Souichirou Kawazoe

Hiroyuki Hisamichi

Akiko Orita

Takashi Kamikubo

Shuichi Sakamoto

Takayuki Suzuki

Kenji Negoro

Kenichi Onda

Akira Toyoshima

Satoshi Hayashibe

Masamichi Okada

Ryo Naito

Eiichi Nakai

Kyoichi Maeno

Hirotsune Itahana

Atsuyuki Kohara

Itsuro Shimada

Kiyoshi Yahiro

A nitrogen-containing six-membered heterocyclic compound having substituents &mdash;X&mdash;A&mdash;R , &mdash;N(R )-(Ph substituted by R ), and &mdash;CONH , a salt thereof, a prodrug thereof, and a Syk inhibitor containing the same as an active ingredient. (In the formula, A: a (substituted) lower alkylene, a (substituted) arylene, or the like; X: NR , CONR , NR CO, O, or S; R , R : H, a lower alkyl, &mdash;CO-lower alkyl, or &mdash;SO -lower alkyl; R : H, a (substituted) lower alkyl, &mdash;O-lower alkyl, &mdash;S-lower alkyl, &mdash;O-aryl, nitro, cyano, or the like; R : &mdash;CO H, &mdash;CO -lower alkyl, -lower alkylene-CO H, &mdash;NH , -alkylene-NH or the like.

Heterocyclecarboxamide derivative

Thiazolobenzoimidazole derivatives

Pyrimidine-5-carboxamide derivatives

Growing community of inventors

Ibaraki, Japan

Kazuhito Tanabe