The University of Tokyo

Kazuhisa Hirabayashi

Tetsuo Nagano

Kenjiro Hanaoka

Takahiro Egawa

Yuichiro Koide

Yuko Toki

A compound represented by the formula (I) (Rrepresents hydrogen atom or a monovalent substituent; Rand Rrepresent hydrogen atom, an alkyl group, or a halogen atom; Rand Rrepresent an alkyl group or an aryl group; Rand Rrepresent hydrogen atom, an alkyl group, or a halogen atom; Rrepresent hydroxy group or a dialkoxyboranetriyl group; and X represents silicon atom, germanium atom, or tin atom), which is a novel fluorophore usable as a mother nucleus of an off/on type fluorescent probe not utilizing the intramolecular photoinduced electron transfer.

Fluorescent probe

A compound represented by the formula (I) [Rrepresents hydrogen atom or a substituent; R, R, R, and Rrepresent hydrogen atom, an alkyl group, a halogen atom, or a hydrophilic substituent; Rand Rrepresent an alkyl group or an aryl group; Rand Rrepresent a group cleaved by contact with an object substance for measurement; and X represents silicon atom, germanium atom, or tin atom] or a salt thereof, which is useful as a fluorescent probe that emits red fluorescence by contact with an object substance for measurement. 

Growing community of inventors

Tokyo, Japan

Kazuhisa Hirabayashi