Toray Industries, Inc.

Other

Nanotheta Co., Ltd.

Inoue, Kanji

Kazuhiro Tanahashi

Masaki Fujita

Koji Kadowaki

Megumi Nakanishi

Satoshi Yamada

Yuka Sakaguchi

Hirokazu Sakaguchi

Yasufumi Yamamura

Taisuke Kogawa

Kanji Inoue

Shinji Takeoka

Yoshiyuki Ueno

Hiroshi Takahashi

Hiroshi Tsuchikura

Nobuaki Tanaka

Tomoyuki Horiguchi

Akihiro Saito

Takahiro Yagi

Toru Arakane

Naotoshi Tomita

Toshinori Fujie

Kenichi Harimoto

So Kakiyama

Hiroyuki Sugaya

Atsushi Murata

Kosaku Takeuchi

Yoshihiro Naruse

Makito Yokoe

Kohei Yamashita

Motonori Hochi

Ichiro Kumo

Shinya Ohtsubo

Giman Jung

Yoshitake Takahashi

Shigehisa Wada

Norikazu Tabata

Akihiko Ito

Kazuyuki Kidoba

Koji Okabayashi

Yuichi Koyamatsu

Kazuya Fujita

Ryo Matsuo

Shoichiro Suzuki

Yoshinori Kakizawa

Toshihiko Kuroda

Nobuyuki Kuroki

Kyohei Yamashita

Ai Suzuki

Shinya Otsubo

Satoko Yamada

Kota Hatta

Takayuki Kaneko

Asanori Shimada

Shuji Sekiguchi

Kanta Tanabe

Yuya Ishiduka

Masaaki Fujita

Giman Toray Koshigoe-Shataku Jung

Shuji Moriguchi-Kata Sekiguchi

Toshihiko Toray Kamakurayama-Ryo 401 Kuroda

Chisa Kuga

A biodegradable block copolymer has high conformability and excellent degradability. The block copolymer including a polyalkylene glycol block and a polyhydroxyalkanoic acid block, wherein the mass ratio of the polyalkylene glycol block with respect to the total mass is 10 to 60%; the carbonyl carbon has a carbon nuclear relaxation time T1ρ of not more than 20 ms; and the block copolymer satisfies Equation (1): χ=χ1×χ2>20 (1) χ1: crystallization rate of the polyalkylene glycol block; χ2: crystallization rate of a poly-A block, wherein A represents, among the repeat units contained in the polyhydroxyalkanoic acid block, a repeat unit whose homopolymer composed of the same repeat units has a highest crystallization rate.

Biodegradable block copolymer

A polymer composition contains polylactic acid and a dilactide/ε-caprolactone copolymer, in which a content of the polylactic acid relative to a total of 100 mass % of the polylactic acid and the dilactide/ε-caprolactone copolymer is 20 to 40 mass %, and in which the dilactide/ε-caprolactone copolymer satisfies (1) an R value represented by a following formula is 0.45 or more and 0.99 or less: where [A] is a molar fraction (%) of a dilactide residue in the dilactide/ε-caprolactone copolymer, [B] is a molar fraction (%) of an ε-caprolactone residue in the dilactide/ε-caprolactone copolymer, and [AB] is a molar fraction (%) of a structure in which a dilactide residue and an ε-caprolactone residue are adjacent to each other (A-B and B-A) in the dilactide/ε-caprolactone copolymer, and (2) at least one of the dilactide residue and the ε-caprolactone residue has a degree of crystallization of less than 14%.

Polymer composition, molded body, and nerve regeneration inducing tube

A cylindrical body for an implant is capable of maintaining a high patency rate by achieving a good antithrombogenicity, a low swelling property and a low Young's modulus. A cylindrical body for an implant includes: a cylindrical substrate having an elongation rate in the longitudinal direction, as measured under a tensile load of 20 N, of from 5 to 100%; and a block copolymer composed of a polyalkylene glycol block(s) and a polyhydroxyalkanoic acid block(s); wherein the ratio of the mass of the polyalkylene glycol with respect to the total mass of the block copolymer is 5 to 25%; and a film composed of the block copolymer has a Young's modulus of 200 MPa or less.

Cylindrical member for implantation

A tubular structure has succeeded in achieving excellent puncture resistance as well as maintenance of flexibility in a base by covering the base with a cover having excellent flexibility. The tubular structure includes a tubular base and a cover which covers the base, wherein the cover includes a copolymer containing a silicone monomer and a polymerizable monomer having a fluoroalkyl group(s) as monomer units.

Cylindrical structure

There is provided a plain-weave fabric excellent in low air permeability and waterproofness. Further, there is provided a stent graft excellent in low water permeability mechanical properties and catheter storage capacity, including the plain-weave fabric as a graft substrate. A plain-weave fabric woven by interlacing weaving yarns in warp and weft, in which weaving yarns YA and YB arranged in the same direction have different crimp ratios A and B, respectively, a relationship thereof satisfies Formula 1, and the crimp ratio B is 4% or more, and the plain-weave fabric is preferably used for a stent graft; A≥B×1.2.

Plain-weave fabric, method for manufacturing same, and stent graft

A tubular woven fabric is useful as a transport hose for a fluid or a powder, as a protective hose for linear bodies such as wires, cables and conduits, as a tubular filter, or as a base material of a vascular prosthesis. The tubular woven fabric includes warp yarns and weft yarns interwoven with each other, the tubular woven fabric having an outer diameter with a variation of within 10% along the warp direction and satisfying the formula:(2&#x2212;1)/1&#x2264;0.1.

Tubular woven fabric

A medical material uses a nickel-titanium alloy wherein a polyelectrolyte has a reduced thickness while a sufficient amount of an antithrombogenic compound for production of a therapeutic effect is supported. The medical material in which a porous surface is formed on a nickel-titanium alloy to allow infiltration of a polyelectrolyte into the pores, to thereby reduce the thickness of the polyelectrolyte exposed on the surface of the nickel-titanium alloy while allowing supporting of a sufficient amount of an antithrombogenic compound due to contribution of the polyelectrolyte infiltrate.

Antithrombotic medical material using nickel titanium alloy

The present invention provides a hollow fiber membrane module which makes it possible to concentrate incubated platelets by efficiently removing water from an incubated platelet suspension liquid containing incubated platelets while suppressing deterioration of the function of the incubated platelets. The present invention provides an incubated platelet concentration module in which a plurality of hollow fiber membranes each having pores with an average pore diameter of 2 &#x3bc;m or less on a surface of the hollow fiber membrane are packed in a casing having at least one inlet for supplying an incubated platelet suspension liquid before concentration into the hollow fiber membranes, wherein a value (X/Y1) obtained by dividing a total cross-sectional area (X) of the plurality of hollow fiber membranes by a total cross-sectional area (Y1) of the least one inlet is 4.0 or less.

Incubated platelet concentration module and method for producing platelet preparation using same

A polyester copolymer has two types of ester bond-forming monomer residues as main structural units when the two types of ester bond-forming monomers are defined as 'monomer A' and 'monomer B', respectively, the polyester copolymer satisfies (1) and (2): (1) an R value represented by equation:value=[]/(2[][])&#xd7;100[A]: mole fraction of monomer A residues in the polyester copolymer [% by mol], [B]: mole fraction of monomer B residues in the polyester copolymer [% by mol], and [AB]: mole fraction of a structure in which the monomer A residues and the monomer B residues are adjacent to each other (A-B and B-A) in the polyester copolymer [% by mol], is 0.45 or more and 0.99 or less; and (2) a crystallization rate of at least one of the monomer A residues and the monomer B residues is less than 14%.

Polyester copolymer and method of producing same

A material for adhesion prevention can be adhered to biological tissue with certainty and has improved tissue adhesiveness and biodegradability. Such material for adhesion prevention is composed of: a 1- to 1,000-&#x3bc;m-thick water-soluble support layer comprising a water-soluble polymer; and a 1- to 1,000-&#x3bc;m-thick adhesion prevention layer comprising a biodegradable polymer. The biodegradable polymer has a structure in which a branched polyalkylene glycol comprising 3 to 8 terminal hydroxyl groups per molecule is bound to a polyhydroxy alkanoic acid, and a mass ratio of the branched polyalkylene glycol relative to the total mass is 1% to 30%.

Material for adhesion prevention

An antithrombogenic metallic material includes a metallic material whose surface is coated with a coating material, the coating material containing: a phosphonic acid derivative or a catechol derivative; a polymer containing, as a constituent monomer, a compound selected from the group consisting of alkyleneimines, vinylamines, allylamines, lysine, protamine, and diallyldimethylammonium chloride; and an anionic compound containing a sulfur atom and having anticoagulant activity; the polymer being covalently bound to the phosphonic acid derivative or the catechol derivative, the phosphonic acid derivative or the catechol derivative being bound to the metallic material through a phosphonic acid group or a catechol group thereof, wherein the abundance ratio of nitrogen atoms to the abundance of total atoms as measured by X-ray photoelectron spectroscopy (XPS) on the surface is 4.0 to 13.0 atomic percent.

Antithrombotic metallic material

A treatment aiding device includes a flexible shaft; a filter; linear supporting members; an elastomer member composed of an elastomer in which a penetrating hole is formed, which elastomer member is arranged in the proximal side relative to the opening section of the filter such that the shaft penetrates the penetrating hole, wherein the outer diameter of the end face in which the penetrating hole is formed is larger than the outer diameter of the opening-section side of the filter when the filter is closed; and an outer tube in which a penetrating hole is formed, which outer tube is arranged in the proximal side relative to the opening section of the filter such that the shaft penetrates the penetrating hole in a state which allows movement of the shaft in the longitudinal direction; wherein the elastomer member is fixed in the distal side of the outer tube.

Endovascular treatment assistance tool

An artificial blood vessel is composed of a cylindrical multiple-woven fabric structure allowing only a small amount of blood leakage and can achieve both antithrombogenicity and cellular affinity. The artificial blood vessel includes a cylindrical fabric structure in which a cylindrical fabric whose inside contacts blood is arranged, wherein the cylindrical fabric is a fabric prepared by interlacing a plurality of warp yarns and a plurality of weft yarns with each other into a cylindrical shape; the warp yarns and the weft yarns constituting the cylindrical fabric include a multifilament yarn having a single yarn fineness of not more than 0.50 dtex, and are bound to an antithrombogenic material; the antithrombogenic material forms an antithrombogenic material layer having a thickness of 1 to 600 nm inside the cylindrical fabric; and the water permeability under conditions where a pressure of 16 kPa is applied to the inner surface is less than 300 mL/cm/min.

Artificial blood vessel

A polymer film can be adjusted to movement or a fine uneven surface of a living body and has excellent ability to adhere to a biological tissue. The polymer film includes a block copolymer having a structure in which branched polyalkylene glycol and polyhydroxyalkanoic acid are bound to each other, wherein the polymer film has a film thickness of 10 to 1000 nm. The branched polyalkylene glycol has at least three terminal hydroxyl groups per molecule, the mass percentage of the branched polyalkylene glycol relative to the total mass of the block copolymer is 1% to 30%, and a value obtained by dividing the average molecular weight of polyhydroxyalkanoic acid in the block copolymer by X that is the number of terminal hydroxyl groups present per a single molecule of the branched polyalkylene glycol is 10000 to 30000.

Polymer film and antiadhesive material using the same

An endovascular treatment aiding device is an endovascular treatment aiding device including a flexible shaft; a filter fixed to the shaft such that an opening section is formed in the proximal side, wherein a ring having elastic restoring force is fixed to the opening section, which filter is capable of being opened and closed in an umbrella-like manner, and is in a conical shape having a bottom formed by the ring when the filter is open; and a linear supporting member fixed to the ring and a part of the shaft such that they are connected to each other, which linear supporting member enables closing the filter by application of an external force to the proximal side; wherein coils formed with a radio-opaque material is/are wound around the ring; when the filter is closed, a plurality of mountains pointing toward the distal side and a plurality of valleys pointing toward the proximal side are alternately formed in the ring to form a shape in which the mountains are positioned close to each other, and the valleys are positioned close to each other; and the coils are arranged on the ring such that the coils contain the positions fixed by the supporting member on the ring, but do/does not contain the positions of the peaks of the mountains and the peaks of the valleys.

Endovascular treatment aid

Growing community of inventors

Otsu, Japan

Kazuhiro Tanahashi