Otsuka Pharmaceutical Company, Limited

Kazuhiro Ohdachi

Yasuhiro Menjo

Keizo Kan

Shigekazu Fujita

Hokuto Yamabe

Satoshi Matsuda

Hideto Fujiwara

Masatoshi Takuwa

Taiki Hanari

Tatsuya Urushima

Hideki Hayashi

Yusuke Fujimori

Kurumi Mineno

Yuki Sakamoto

Ryosuke Taga

Naoya Makita

Noritaka Koseki

Provided is a novel heterocyclic compound having an aryl hydrocarbon receptor antagonist activity and useful for the promotion of platelet production, the compound being represented by the general formula [I]: wherein ring A, ring B, R, R, R, R, n, and X are as defined above, or a salt thereof.

Heterocyclic compound

The present invention provides novel benzazepine compounds of Formula (1), or salts thereof, having vasopressin Vand Vantagonisms, and medical uses thereof. In the formula, Ris optionally substituted Calkyl, etc.; L is &#x2014;C(&#x2550;O)&#x2014;NH&#x2014;, etc.; Ring Ais a hydrocarbon ring, etc.; Ring Ais a hydrocarbon ring, etc.; and each of Rings Aand Amay have at least one substituent.

Benzazepine derivatives

The present invention provides novel benzazepine compounds of Formula (1), or salts thereof, having vasopressin Vand Vantagonisms, and medical uses thereof. In the formula, Ris optionally substituted Calkyl, etc.; L is &#x2014;C(&#x2550;O)&#x2014;NH&#x2014;, etc.; Ring Ais a hydrocarbon ring, etc.; Ring Ais a hydrocarbon ring, etc.; and each of Rings Aand Amay have at least one substituent. 

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Osaka, Japan

Kazuhiro Ohdachi