M Bio Technology Inc.

Seikagaku Corporation

National Institute of Infectious Diseases

Ube Industries, Inc.

Kazuhiro Matsuda

Naoki Yamamoto

Yuko Sasaki

Yoshichika Arakawa

Yuko Shingu

Koji Ichiyama

Sachie Matsuda

Ryo Harasawa

Yoshihiro Nishida

Norio Katayama

Yasuo Endo

Nobuo Nomura

The present invention provides a novel glyceroglycolipid produced by. The glyceroglycolipid can be used as a diagnostic marker for a disease caused by

Method for producing an isolated monoclonal antibody specifically binding to a glycolipid antigen of

Disclosed is a vaccine which has a high therapeutic effect oninfection and is highly safe. For the purpose of developing effective therapeutic methods forinfection,-mimic particles which are effective as a vaccine forinfection are provided, and also provided are bacterium-mimic particles including common bacteria. Bacterium-mimic particles such as-mimic particles can be provided by producing liposome particles in which a lipid antigen specific to a pathogenic bacterium such asis contained as a liposome-constituting lipid component. The administration of the-mimic particles enables the induction of a potent immunological activity in living bodies. The-mimic particles can be used as an excellent vaccine for the prevention or treatment ofinfection.

Vaccine for mycoplasma infection

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Mouse is immunized with an antigen of a lipid fraction originating from . Its spleen cells are fused with mouse myeloma cells to prepare hybridomas. A hybridoma is selected, which produces a monoclonal antibody having reaction specificity to GGPL-III that is a phosphocholine-containing glycoglycerolipid specific to is detected by using the obtained antibody.

Glycoglycerophospholipid, antibody thereagainst, and method for detecting mycoplasma

Glycoglycerophospholipid, antibody thereagainst, and method for

The invention is directed to the compound 1'-[2,3-Bis(hexadecanoyloxy)propyl]-d-glycopyranos-6'-yl-2'-(trimethylammo nium)ethylphosphate which is a phosphorylcholine-containing glyceroglycolipid useful for detecting the presence of Mycoplasma fermentans in cells or microorganisms.

Phosphorylcholine-containing glyceroglycolipid

Growing community of inventors

Tokyo, Japan

Kazuhiro Matsuda