Fujifilm Corporation

Terumo Kabushiki Kaisha

Topcon Corporation

Kazuhiro Hirota

Kaku Irisawa

Tadashi Kasamatsu

Hiroyasu Ishii

Haruyasu Nakatsugawa

Kazuhiro Tsujita

Yoshihiro Seto

Taiji Iwasaki

Hirotaka Watano

Tatsuyuki Denawa

Takeya Meguro

Tsuyoshi Matsumoto

Keiji Tsubota

Dai Murakoshi

Yoshiro Imai

Mitsutoshi Yaegashi

Hiroyuki Yagami

Takuji Tada

Toyokazu Horiike

Katsuaki Kamoike

Taro Tsunoda

A management system including at least one processor, wherein the processor is configured to acquire a captured image obtained by imaging an outer surface of each of plural sample containers which contains a sample and in which discrimination information for discriminating a subject from whom the sample is collected is given to the outer surface, and associate a test result related to the sample contained in each of the sample containers with a test order in which information of a discrimination image including the discrimination information is registered in advance for each subject, based on the captured image and the test order.

Management system and management method

A management system including at least one processor, wherein the processor is configured to acquire an image obtained by imaging a sample container containing a sample, recognize relevant information related to reliability of a test result related to the sample based on the image, and derive reliability information indicating the reliability of the test result related to the sample based on the recognized relevant information.

A photoacoustic image evaluation apparatus includes a processor configured to acquire a first photoacoustic image generated at a first point in time and a second photoacoustic image generated at a second point in time before the first point in time, the first and second photoacoustic images being photoacoustic images generated by detecting photoacoustic waves generated inside a subject, who has been subjected to blood vessel regeneration treatment, by emission of light into the subject; acquire a blood vessel regeneration index, which indicates a state of a blood vessel by the regeneration treatment, based on a difference between a blood vessel included in the first photoacoustic image and a blood vessel included in the second photoacoustic image; and display the blood vessel regeneration index on a display.

Photoacoustic image evaluation apparatus, method, and program, and photoacoustic image generation apparatus

Provided are a photoacoustic image generation apparatus, a photoacoustic image generation method, and a photoacoustic image generation program that can perform a more appropriate reconstruction process regardless of the type of probe, without causing a reduction in the speed of an arithmetic process. It is identified whether a probe that detects photoacoustic waves and outputs a photoacoustic wave detection signal is a probe in which detection elements are arranged by a coordinate system using polar coordinates or a probe in which detection elements are arranged by a rectangular coordinate system. In a case in which the probe is identified as the probe in which the detection elements are arranged by the coordinate system using the polar coordinates, a time domain reconstruction process is selected to generate a photoacoustic image.

Photoacoustic image generation apparatus, photoacoustic image generation method, and photoacoustic image generation program

A Q switch is vibrated by applying a first voltage, and pulsed laser light is emitted by applying a second voltage to the Q switch at a point in time at which a preset delay time has passed from the start of emission of excitation light. Then, in this case, a time which is within a period, for which the vibration of the Q switch continues, and at which the intensity of the pulsed laser light periodically changing due to the vibration of the Q switch is maximized in a case where a point in time of application of the second voltage to the Q switch is changed is set as the delay time.

Laser device and photoacoustic measurement apparatus

In a laser device that emits pulsed laser light by emitting excitation light to a laser medium in a state in which a first voltage is applied to a Q switch and changing the voltage applied to the Q switch from a first voltage to a second voltage after the emission of the excitation light, the application start timing of the first voltage during a normal operation is set to a timing at which the intensity of the pulsed laser light periodically changing due to the vibration of the Q switch is maximized.

There is provided a photoacoustic measurement apparatus including a laser light source unit that has a flash lamp for emitting excitation light and a laser rod for emitting laser light in response to incidence of the excitation light, an excitation light source power supply unit that has a capacitor bank for supplying a voltage to the flash lamp, an IGBT for controlling an output of the voltage charged in the capacitor bank to the flash lamp, a discharge control circuit for generating a driving pulse for driving the IGBT, and a pulse width limiting circuit for limiting a pulse width of the driving pulse output from the discharge control circuit, the pulse width limiting circuit being formed of a passive element, and a photoacoustic wave detection unit that detects photoacoustic waves generated inside a subject by emission of light emitted from the laser light source unit to the subject.

Photoacoustic measurement apparatus

To obtain an absorption distribution from a detected signal with a practical device. Light is applied to a subject, and a photoacoustic signal generated in the subjectA photoacoustic is detected. From the detected photoacoustic signal, a light differential waveform, which is a differential waveform of a temporal waveform of the light applied to the subject, is deconvolved. As a result of this deconvolution, an absorption distribution is obtained.

Device and method for processing photoacoustic signal

A photoacoustic imaging method is provided that can prevent the surface of the subject from appearing in an image when a part to be observed at a position deeper than the surface of the subject is imaged. The photoacoustic imaging device includes a unit for outputting pulsed light toward the subject, and generating photoacoustic data by detecting photoacoustic waves emitted from the subject exposed to the light. The photoacoustic imaging device also includes a region detection unit that detects a near-surface region of the subject based on the photoacoustic wave detection signals, and a correcting unit that attenuates (which encompasses removing) information of the near-surface region found by the region detection unit when the part to be observed is displayed.

Photoacoustic imaging method and device

There is provided a photoacoustic measurement apparatus capable of appropriately detecting a single failure state even in the single failure state so that it is possible to prevent an operation in the single failure state from continuing. There are included: a laser light source having a flash lamp and a laser medium; an excitation light source power supply having a capacitor for supplying a charge voltage to the flash lamp, a charging circuit for charging the capacitor, a first voltage dividing circuit and a second voltage dividing circuit for dividing a voltage charged in the capacitor, and a failure detection circuit that detects a failure by comparing voltages obtained by voltage division of the first voltage dividing circuit and the second voltage dividing circuit; and an ultrasound probe that detects photoacoustic waves generated inside a subject by emission of light emitted from the laser light source to the subject.

A probe has a light guide unit that guides the measurement light, an acoustic wave detection unit that detects a photoacoustic wave, and a storage unit that stores light intensity profile information that represents the light intensity profile of the measurement light emitted by the probe, and transmits a signal of the photoacoustic wave detected by the acoustic wave detection unit to the signal processing unit in a state in which the probe is mounted in the apparatus body. The apparatus body has a reading unit that reads the light intensity profile information from the storage unit, and the intensity adjusting unit adjusts the intensity of the measurement light employing the light intensity profile information read by the reading unit.

Photoacoustic measurement apparatus and probe for photoacoustic measurement

After light has been output to a subject to be examined, a photoacoustic wave induced in the subject by the output light is detected. It is assumed that at least one virtual detector element is present outside of a real detector, and dummy data corresponding to the at least one virtual detector element are added to photoacoustic data in which pieces of data of the photoacoustic wave detected by the detector are arranged in accordance with the positions of detector elements. A photoacoustic image is generated by reconstructing the photoacoustic data to which the dummy data have been added by using a Fourier transform method.

Photoacoustic image generation apparatus and method

In a solid-state laser device and a photoacoustic measurement device including the solid-state laser device, the distance between a laser rod and a flash lamp is narrowed. A shielding lid shields mirrors and an optical path of laser light from the outside. A first portion of a frame body of a laser chamber is exposed from the shielding lid. A flash lamp stored in the frame body of the laser chamber is able to be removed from and inserted into the first portion of the frame body. A thin film portion having a thickness smaller than the thickness of other portions of the shielding lid is provided in at least a part of a region of the shielding lid covering the optical path of a light beam on the outside in a longitudinal direction from the first portion of the frame body of the laser chamber.

Solid-state laser device and photoacoustic measurement device

A flash lampexcites a laser rod. A Q switchwhich changes the loss of the optical resonator according to the voltage applied is inserted on the optical path of a pair of mirrorsandforming the optical resonator. An optical path shutteris provided on the optical path of laser emission light. In a first operation mode in which laser emission is performed, the optical path shutteris opened and the voltage applied to the Q switchis changed from a high voltage to, for example, 0 V to emit pulsed laser light after the flash lampexcites the laser rod. In a second operation mode in which the laser emission is interrupted and waited for, the optical path shutteris closed and the voltage applied to the Q switchis, for example, 0 V.

Photoacoustic measurement device and laser light source

A photoacoustic measurement deviceincludes a probehaving a light emitting unit that emits measurement light L and a plurality of acoustic wave detection elements, a determination unitthat determines whether a state between the probeand a subject M is a contact state or a non-contact state, and a light intensity control unit (for example, a switching control unitand an intensity switching unit) that controls the intensity of the measurement light such that the measurement light has a first intensity or a second intensity higher than the first intensity, on the basis of the determination result of the determination unit. The determination unitperforms the determination on the basis of the status of a change in a plurality of photoacoustic signals detected by the plurality of acoustic wave detection elements.

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Kanagawa, Japan

Kazuhiro Hirota