Olympus Corporation

Olympus Optical Company, Ltd.

Other

Ebara Corporation

Shionogi Company Limited

Keio University

Archem Inc.

Kazuhiro Hasegawa

Atsuhiro Tsuchiya

Kenichi Koyama

Akitsugu Kagayama

Hideaki Endo

Katsuyoshi Yamaguchi

Ryuichi Hirano

Atsushi Yonetani

Keisuke Tamura

Kenji Karaki

Yoshiyuki Takahashi

Takashi Yoneyama

Hiroshi Itoh

Takashi Ono

Yoshihiro Ue

Taichi Itabashi

Kazunari Tanaka

Takeshi Kanda

Hideyuki Masuyama

Hiroshi Toriumi

Katsutoshi Yamada

Yuichi Fuchu

Hideyuki Yoshida

Yoshiharu Yasuhara

Shu Wakino

Toshihiro Shinosaki

Takayuki Mochizuki

Yutaka Niida

Norito Yoshimura

Sumio Komine

William K Fester

Yoshinari Gahara

Motoaki Komatsu

Hiromasa Kaihatsu

Hiroshi Takasu

Tadashi Nagawa

A moldis a mold for molding a foam body, the mold including: a mold body portion; and a degassing toolattached to the mold body portion. The degassing tool is formed of porous metal, and a surfaceof the degassing tool that is on a side of a cavity of the mold forms part of a molding surface S of the mold.

Mold, degassing tool, and method for producing resin foam

This invention is related to a therapeutic agent for treating chronic kidney disease comprising a substance which inhibits the enzymatic activity of NNMT or suppresses NNMT gene expression, or a method for screening a therapeutic agent for treating chronic kidney disease which targets the NNMT enzyme or NNMT gene.

Pharmaceutical composition for treating chronic kidney disease

An optical-device switching apparatus of a microscope includes a driving motor, and a rotation unit that is rotatably attached to a body and to which optical devices are attached, and a gear apparatus that is located between the driving motor and the rotation unit and transmits power from the driving motor to the rotation unit. The gear apparatus includes a backlash reduction system that reduces backlash.

Optical-device switching apparatus for microscope

A microscope includes a microscope main body, a revolving nosepiece rotatably mounted on the microscope main body and equipped with plural objective lenses, and focusing handles that adjust focal points of the objective lenses. The microscope further includes operation knobs mounted in a vicinity of the focusing handles and configured to move by a predetermined amount in a predetermined directions and an operating-force transmitting mechanism provided between the operation knobs and the revolving nosepiece and configured to transmit, when the operation knobs move, operating force to the revolving nosepiece to cause the movable member to move so that the objective lenses can be switched from one to the other through a single moving operation of the operation knobs by the predetermined amount.

Microscope having an optical-element switching operation unit configured to rotate a movable element equipped with a plurality of optical elements by a single translatory operation

A microscope includes a microscope main body, a revolving nosepiece rotatably mounted on the microscope main body and equipped with plural objective lenses, and focusing handles that adjust focal points of the objective lenses. The microscope further includes operation knobs mounted in a vicinity of the focusing handles and configured to move by a predetermined amount in a predetermined direction, and an operating-force transmitting mechanism provided between the operation knobs and the revolving nosepiece and configured to transmit, when the operation knobs move, operating force to the revolving nosepiece to cause the movable member to move so that the objective lenses can be switched from one to the other through a single moving operation of the operation knobs by the predetermined amount.

Microscope

A tissue culture microscope apparatus includes a culture unit that includes a chamber in which a specimen is put, and maintains the chamber at a predetermined temperature to culture the specimen; an observation unit that forms an observation image of the specimen put in the chamber; and a liquid supply unit that stores a liquid in a protrusion portion penetrating into a wall of the chamber and protruding to an inside of the chamber, matches a temperature of the liquid with the temperature of the chamber, and injects the liquid from the protrusion portion to the specimen.

Tissue culture microscope apparatus

A culture microscope apparatus has an illumination unit to apply excitation light to the specimen, a specimen observing portion to observe light generated from the specimen due to the excitation light, and a dimmer unit to dim the excitation light that has penetrated the specimen.

Culture microscope apparatus

An inverted microscope includes a lens holding mechanism which holds an objective lens arranged under a sample and used to form an observation image of the sample; a focusing mechanism which holds the lens holding mechanism on its upper part and moves the objective lens up and down together with the lens holding mechanism; and a microscope main body which serves as a casing including the focusing mechanism therein, and includes an opening allowing an attachment of the focusing mechanism and the lens holding mechanism in its upper wall surface. A size of the lens holding mechanism in a horizontal plane is larger than a size of an image projected onto the horizontal plane of the opening.

Inverted microscope provided with blockage member for preventing spillage of fluid

A culture observation apparatus, which is used for observing a cultured cell while culturing the cell, includes a culture device that cultures the cultured cell, and a microscope used for observing the cultured cell. The culture device includes a first space that is controlled to an environment suitable for culture of the cell, and a second space that is controlled to a lower humidity condition in comparison with the first space. The microscope includes an objective optical unit including an objective lens; the objective optical unit having at least one portion located in the second space, and another portion extending into the first space through an opening formed in a partition wall that separates the first space and the second space, with a gap between the objective optical unit and the partition wall being sealed by a sealing member, and the objective lens includes a plurality of lens groups, with mutual spaces among the lens groups vented to the second space.

Culture observation apparatus

An observation apparatus includes an incident-light illumination optical system, a transmitting illumination optical system, an imaging unit, an input device, a storage unit, an imaging controller, a microscope controller, an imaging information management unit. The imaging information management unit compares an area position, of an imaging area of the imaging unit, indicated by position information input from the input device with an area position stored in the storage unit to determine whether the area position indicated by the position information is stored in the storage unit. When the area position is not stored in the storage unit, the imaging controller controls the imaging unit to image the specimen and to generate an observation image, and stores the observation image in the storage unit. The microscope controller controls one of the optical systems to illuminate the specimen only during an imaging period, when the imaging unit images the specimen.

Observation apparatus and observation method

A culture observation apparatus, which is used for observing a cultured cell while culturing the cell, includes a culture device that forms a culture space which is controlled to be an environment suitable for culturing the cultured cell; a sample tray that holds a container housing the cultured cell and a culture medium; a microscope that serves for observing the cultured cell; a tray holding mechanism that holds the sample tray in the culture space in a detachable manner with good reproducibility; and a shifting mechanism that relatively shifts the sample tray held by the tray holding mechanism and a light axis of the microscope along a plane that is orthogonal to the light axis, wherein the sample tray has a heater used for heating the sample tray, and is electrically connectable to an energy supplying unit that supplies energy to the sample tray.

Culture observation apparatus, sample tray heat-insulating device and lid

An observation apparatus includes a sample tray that holds a container housing a cultured cell and a culture medium and covered with a lid; an observation unit that serves for observation of the cultured cell; and a shifting unit that relatively shifts the sample tray and a light axis of the observation unit along a plane that is orthogonal to the light axis of the observation unit, wherein the sample tray includes a container holding unit that holds the container by utilizing an elastic force, and at least one of the lid and one portion of the lid is made detachable, with the container being held in the sample tray by the container holding unit.

Observation apparatus

Provided is a microscope lens barrel including a collecting lens and a deflecting optical system. The collecting lens emits observation light toward the deflecting optical system. The deflecting optical system includes a first reflecting plane, a second reflecting plane, a third reflecting plane, and a fourth reflecting plane, and deflects the observation light emitted from the collecting lens. The first reflecting plane transmits the observation light incident from one direction and reflects the observation light incident at an angle from another direction. The second reflecting plane reflects the observation light transmitted through the first reflecting plane and makes the reflected observation light incident on the first reflecting plane at an angle. The third reflecting plane reflects the observation light reflected by the first reflecting plane in a direction of the second reflecting plane. The fourth reflecting plane reflects the observation light reflected by the third reflecting plane in a direction perpendicular or substantially perpendicular to an optical axis of the collecting lens in a direction from the optical axis of the collecting lens toward the third reflecting plane.

Microscope lens barrel

A digital camera for an optical apparatus according to an aspect of the present invention comprises a solid-state imaging device which picks up an image of a target object, a solid-state imaging device cooling part configured to cool the solid-state imaging device, and a sealing part which includes a printed board for wiring for electric signals, and seals the solid-state imaging device and the solid-state imaging device cooling part.

Digital camera for an optical apparatus including a cooling mechanism for a solid-state imaging device

Growing community of inventors

Hachioji, Japan

Kazuhiro Hasegawa