Fujifilm Corporation

Kazuhei Kaneko

Kousuke Watanabe

Yoshinori Kanazawa

Kouitsu Sasaki

Tomoaki Yoshioka

Naoyuki Hanaki

Hiroyuki Chiku

Yosuke Yamamoto

Kazuhiro Hamada

Makoto Takahashi

Daisuke Nakagawa

Mika Imamura

Motomasa Takahashi

Hirotaka Satou

Yuji Yoshimitsu

Hirofumi Omura

Keita Tanaka

Nobutaka Fukagawa

Hiyoku Nakata

Keiko Makita

Akihiro Asakura

Takeru Shigemura

There are provided a method of producing a nucleic acid compound, in which a nucleic acid compound in which any one of a 3-position or a 5-position of a ribose structure is protected by a structure represented by Formula (1), and the nucleic acid compound. In Formula (1), a ring A represents a condensed polycyclic aromatic hydrocarbon ring or an aromatic heterocyclic ring, Y's each independently represent —OCR—, —NRCR—, or —SCR—, R's each independently represent a hydrogen atom, an alkyl group, an aromatic group, or an aromatic group-substituted alkyl group, k represents an integer of 1 to 5, R's are each independently an aliphatic hydrocarbon group or an organic group having an aliphatic hydrocarbon group, at least one aliphatic hydrocarbon group in k pieces of R's has 12 or more carbon atoms, and the ring A may further have a substituent in addition to Yand R.

Method of producing nucleic acid compound, and nucleic acid compound

Provided are a method for producing a peptide compound including a step of using a condensed polycyclic aromatic hydrocarbon compound represented by Formula (1); a protective group-forming reagent including the compound; and the compound. In Formula (1), a ring A represents a condensed polycyclic aromatic hydrocarbon ring, Y's each independently represent —CHOH, —CHNHR, —CHSH, or —CHX, where R represents a hydrogen atom, an alkyl group, or an aralkyl group, and Xrepresents Cl, Br, or I, k represents an integer of 1 to 5, n represents 1 or 2, and R's each independently represent an aliphatic hydrocarbon group or an organic group having an aliphatic hydrocarbon group.

Method for producing peptide compound, protective group-forming reagent, and condensed polycyclic aromatic hydrocarbon compound

An object of the present invention is to provide a photoelectric conversion element that exhibits excellent external quantum efficiency and responsiveness to light at all wavelengths in a red wavelength region, a green wavelength region, and a blue wavelength region. Another object of the present invention is to provide an imaging element, an optical sensor, and a compound related to the photoelectric conversion element. The photoelectric conversion element includes, in the following order, a conductive film, a photoelectric conversion film, and a transparent conductive film, in which the photoelectric conversion film contains a compound represented by Formula (1).

Photoelectric conversion element, imaging element, optical sensor, and compound

An object of the present invention is to provide a solid phase carrier for carrying a bioactive substance, which achieves both the high non-specific adsorption inhibitory effect and high ligand binding amount. Another object of the present invention is to provide a kit for measuring a measurement target substance in a biosample, which includes the solid phase carrier. According to an embodiment of the present invention, a solid phase carrier for carrying a bioactive substance is provided which includes a copolymer present on a surface of the solid phase. The copolymer has a structural unit in which a hydrophilic group and a bioactive substance-reactive group are bonded to an acidic amino acid-derived group through a predetermined linking group.

Solid phase carrier and kit

An object of the present invention is to provide a kit for measuring a measurement target substance and a method for measuring a measurement target substance, which can exhibit a high noise suppression effect. According to the present invention, there is provide a kit for measuring a measurement target substance in a biological sample, which includes a luminescently labeled particle that has a first binding substance having a binding property to a measurement target substance, a substrate that has a detection area on a metal film having a second binding substance having a binding property to any one of the measurement target substance or the first binding substance, and a non-luminescent high molecular particle containing a predetermined structural unit.

Kit for measuring measurement target substance and method for measuring measurement target substance

Provided are a method for producing a peptide compound including a step of using an aromatic heterocyclic compound represented by Formula (1); a protective group-forming reagent including the compound; and the compound. In Formula (1), a ring A represents an aromatic heterocyclic ring, Y's each independently represent —OH, —NHR, —SH, or —X, where Xrepresents Cl, Br, or I, Rand Reach independently represent an aliphatic hydrocarbon group or an organic group having an aliphatic hydrocarbon group, Rs' each independently represent a monovalent aliphatic hydrocarbon group, a (1+c)-valent aromatic group, or a (1+c)-valent heteroaromatic group, where, in a case where both a and c is 0, Ris a monovalent aliphatic hydrocarbon group, and the number of carbon atoms in at least one aliphatic hydrocarbon group of R, R, or Ris 12 or more

Method for producing peptide compound, protective group-forming reagent, and aromatic heterocyclic compound

An object of the present invention is to provide a kit, a method, and a reagent which prevent the problem of false positive due to nonspecific adsorption, suppress the increase in noise to be generated, and are capable of achieving high-precision measurement of progesterone in a wide concentration range from a low concentration to a high concentration, in the measurement of progesterone in a biological sample. The present invention provides a progesterone measuring kit including a first particle having a label and modified with a first binding substance, a second particle having no label and modified with a second binding substance, a flow channel, and a substrate, in which the first particle contains a compound represented by Formula (1) and a particle, and an average particle diameter of the first particles is 50 to 250 nm, an average particle diameter of the second particles is 70 to 500 nm, and the average particle diameter of the second particles is larger than the average particle diameter of the first particles. Each symbol in the formula has the meaning described in the present specification.

Progesterone measuring kit, progesterone measuring method, and progesterone measuring reagent

An object of the present invention is to provide a luminescent particle having an emission maximum wavelength in a long wavelength range of 680 nm or longer and exhibiting a high quantum yield; and a compound having an emission maximum wavelength in a long wavelength range of 680 nm or longer and exhibiting a high quantum yield in the particles. According to the present invention, provided is a luminescent particle containing at least one kind of compound represented by Formula (1) (definitions of substituents in the formula are as set forth in the description) and a particle.

Luminescent particle and compound

Provided are any one of the following fluorescent compounds and a fluorescent labeled biological substance having this fluorescent compound. However, in a case where the ring βand the ring βare a 6-membered ring, and Land Lare an arylene group, Ris not an aryl group substituted with a linear alkyl group having 18 or more carbon atoms. In addition to the regulation of the ring β, the ring β, L, and L, in a case where Rhas a substituent having a dipyrromethene boron complex structure, the dipyrromethene boron complex structure has a structure in which a dipyrromethene skeleton is coordinately bonded to a boron atom in the tridentate or tetradentate coordination.

Fluorescent compound and fluorescent labeled biological substance using the same

An object of the present invention is to provide a kit and a method which are capable of measuring a measurement target substance in a biological sample with high precision in a measurement range from a low concentration range to a high concentration range. According to the present invention, there is provided a kit for measuring a measurement target substance in a biological sample, including a labeled particle having a first binding substance capable of binding to a measurement target substance in a biological sample, and a substrate having a second binding substance capable of binding to any one of the measurement target substance or the first binding substance, in which the labeled particle is a luminescent labeled particle containing at least one kind of compound represented by Formula (1) and a particle. Each symbol in Formula (1) has the meaning described in the present specification.

Kit and method for measuring measurement target substance in biological sample

An object of the present invention is to provide a kit, a method, and a reagent which prevent the problem of false positive due to nonspecific adsorption, suppress the increase in noise to be generated, and are capable of achieving high-precision measurement of a measurement target substance in a wide concentration range from a low concentration to a high concentration. According to the present invention, there is provided a kit for measuring a measurement target substance, the kit including: a first particle having a label and modified with a first binding substance capable of specifically binding to a measurement target substance; a second particle having no label and modified with a second binding substance incapable of specifically binding to the measurement target substance; a flow channel for flowing the first particle and the second particle; and a substrate having a third binding substance capable of specifically binding to the measurement target substance or a substance capable of binding to the first binding substance, in which the first particle having a label is a luminescent labeled particle containing at least one kind of compound represented by Formula (1) and a particle. Each symbol in Formula (1) has the meaning described in the present specification.

Kit, method, and reagent for measuring measurement target substance

An object of the present invention is to provide a kit and a method capable of achieving high-precision measurement of a measurement target substance in a biological sample in a wide concentration range from a low concentration to a high concentration. According to the present invention, there is provided a kit for measuring a measurement target substance in a biological sample, the kit including: a labeled particle having a first binding substance capable of binding to the measurement target substance in a biological sample and having a first blocking agent; and a substrate having a second binding substance capable of binding to any one of the measurement target substance or the first binding substance and having a second blocking agent, in which the labeled particle is a luminescent labeled particle containing at least one kind of compound represented by Formula (1) and a particle, and the first blocking agent and the second blocking agent are different from each other.  Each symbol in Formula (1) has the meaning described in the present specification.

Provided are a color conversion composition which contains at least one kind of compound represented by a specific general formula, a compound which is used in the color conversion composition and represented by a specific general formula, and a light emitting device which has a color conversion portion consisting of the color conversion composition and a light source.

Color conversion composition, compound used for same, and light emitting device

An object of the present invention is to provide a wavelength conversion luminescent resin composition that exhibits a high quantum yield, a wavelength conversion member, and a light-emitting element; as well as a method for producing the wavelength conversion luminescent resin composition that exhibits a high quantum yield. The present invention provides a wavelength conversion luminescent resin composition that contains at least one compound represented by Formula (1) and a resin.  The substituents in the formula are as defined in the present specification.

Wavelength conversion luminescent resin composition, method for producing wavelength conversion luminescent resin composition, wavelength conversion member, and light-emitting element

An object of the present invention is to provide a luminescent particle having an emission maximum wavelength in a long wavelength range of 680 nm or longer and exhibiting a high quantum yield; and a compound having an emission maximum wavelength in a long wavelength range of 680 nm or longer and exhibiting a high quantum yield in the particles. According to the present invention, provided is a luminescent particle containing at least one kind of compound represented by Formula (1) (definitions of substituents in the formula are as set forth in the description) and a particle. 

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Ashigarakami-gun, Japan

Kazuhei Kaneko