Meiji Seika Kaisha, Ltd.

Meiji Seika Kabushiki Kaisha

Kazue Yasufuku

Seiji Shibahara

Fumiya Hirano

Tomoya Machinami

Yasukatsu Yuda

Takashi Tsuruoka

Kiyoaki Katano

Motohiro Nishio

Shigeharu Inoye

Yuji Matsuhashi

A novel benzothiazole or benzimidazole derivative represented by formula (I) ##STR1## wherein X represents a sulfur atom or a NH group; R.sup.1 represents a hydrogen atom, a lower alkoxy group, a chlorine atom, a bromine atom or an iodine atom; R.sup.2 represents a hydrogen atom a substituted or unsubstituted lower alkyl group, a vinyl group, an aryl group or an acyl group; m is an integer of 1, 2 or 3; and n is an integer of 0, 1 or 2, which shows an excellent acid secretion suppressing effect and gastric mucosa protecting effect, and an antiulcer agent containing the same as an active ingredient.

Benzothiazole and benzimidazole derivatives and antiulcer agent

A thiazole or imidazole derivative having the general formula (I): ##STR1## wherein: R.sup.1 and R.sup.2, which may be the same or different, each independently represent a hydrogen atom, or a phenyl or heteroaryl group, or R.sup.1 and R.sup.2 may together form a benzene ring which may be optionally substituted by a halogen atom or a lower alkyl optionally substituted by a halogen atom, lower alkoxy or nitro group;

Thiazole and imidazole derivatives and antiulcer composition containing

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Yokohama, Japan

Kazue Yasufuku