Panasonic Corporation

Panasonic Intellectual Property Management Co., Ltd.

Kazuaki Nishio

Nozomu Matsukawa

Shigeo Yoshii

Ichiro Yamashita

Masahiko Shioi

Hiroto Yanagawa

Emina Ikeuchi

Noriko Shimba

Kohei Hara

Shinya Kumagai

Mitsuhiro Okuda

Takuro Matsui

A pathogen detection apparatus includes an obtainer that measures a body temperature of a subject and outputs information indicating the body temperature, a collector that performs a pathogen collection operation for collecting a pathogen carried by the subject or a pathogen in air around the subject, a detector that performs a pathogen detection operation for detecting the pathogen collected by the collector, a notifier that provides a notification indicating a detection result obtained by the detector, and a controller. In a case where the body temperature output by the obtainer is higher than a predetermined threshold value and the detection result obtained by the detector is negative, the controller controls the detector to perform another pathogen detection operation for detecting a pathogen.

Pathogen detection apparatus and pathogen detection method

The present disclosure provides a detection device capable of detecting a low concentration of an analyte with high sensitivity. The detection apparatus according to the present disclosure comprises a metal microstructure on which a first VHH antibody having a property of binding specifically to the analyte is immobilized and which generate surface plasmon by being irradiated with excitation light, an inlet through which a second VHH antibody and a sample that may contain an analyte are introduced, wherein the second VHH antibody has a property of binding specifically to the analyte and is labeled with a fluorescent substance, a light source for irradiating the metal microstructure to which the second VHH antibody and the sample have been introduced with the excitation light, and a detection unit for detecting the analyte on the basis of fluorescence generated from the fluorescent substance by the irradiation of the excitation light.

Detection device and detection method

Provided is a concentration device suitable for dielectrophoresis. The concentration device comprises a first substrate, a second substrate provided so as to face the first substrate, a flow path formed between the first substrate and the second substrate, a first pillar electrode line disposed in the flow path and including a left-side first pillar electrode L (L), a right-side first pillar electrode R (R), and one second pillar electrode B (B), and a second pillar electrode line disposed in the flow path and including one second pillar electrode A (A). The value of Lis not less than 5 micrometers, where Lis equal to (A&#x2212;A), Arepresents a distance between a second vertex Qof the second pillar electrode A and a center point O; and Arepresents a distance between the first vertex Qof the second pillar electrode B and the center point O.

Concentration device suitable for dielectrophoresis and method for concentrating particles with the same

Provided is a novel peptide capable for binding to carbon. The peptide consists of an amino acid sequence represented by SQMMGHMGHGNMNHMNHGGKFDFHH (SEQ ID NO:01).

Peptide capable for binding to carbon

The present invention provides a novel peptide capable for binding to gold. The peptide consists of an amino acid sequence represented by SQMMGHMGHGNMNHMNHGGKFDFHH (SEQ ID NO: 01).

Peptide capable for binding to gold

The present invention provides a novel peptide capable for binding to iridium. The peptide consists of an amino acid sequence represented by SQMMGHMGHGNMNHMNHGGKFDFHH (SEQ ID NO: 01).

Peptide capable for binding to iridium

The present invention provides a novel peptide capable for binding to rhodium. The peptide consists of an amino acid sequence represented by SQMMGHMGHGNMNHMNHGGKFDFHH (SEQ ID NO: 01).

Peptide capable for binding to rhodium

The present invention relates to a method for detecting an antigen with use of an antibody and an enzyme. Specifically, the present invention provides a method for detecting an antigen without use of a labeled-antibody. the method comprises immersing particles in a first buffer solution which is predicted to contain the antigen; wherein an antibody and a multi-copper oxidase CueO are immobilized on each surface of the particles, and the antibody reacts specifically with the antigen. The method further comprises the following steps recovering the obtained particles; mixing the particles recovered, an oxidation-reduction indicator (reductant), and a second buffer solution so as to prepare a reaction solution; measuring an activity degree of the multi-copper oxidase CueO contained in the reaction solution; determining that the first buffer solution contains the antigen based on the above activity degree.

Method for detecting an antigen

Provided is a method for detecting an antigen without use of a labeled-antibody. A support having an antibody and a multi-copper oxidase CueO immobilized thereon is brought into contact with a first buffer solution containing the antigen, a current is measured by a potentiostat method using the support and a second buffer solution, and when the measured current is greater than or equal to 1.5&#xd7;(blank value), it is determined that the antigen exists. The second buffer solution contains a substrate of the CueO and has an ionic strength falling within a range of not less than 0.3 mM and not more than 1.0 mM.

To provide a method of arranging ferritin by which a high rate of the number of the molecular film spots on which sole ferritin molecule was arranged in effect, with respect to total number of the molecular film spots provided for arranging ferritin (sole arrangement rate) is achieved is objected to. Specifically, in Fer8 ferritin having a sequence excluding 7 amino acids of from the second to the eighth, from an amino acid sequence (Fer0 sequence) translated from a naturally occurring DNA sequence, lysine at positionis substituted with glutamic acid.

Method of arranging ferritin and method of arranging inorganic particles

An object of the present invention is to obtain a zinc oxide-protein complex which can be a source of nanoparticles of zinc oxide utilizing a protein having a cavity inside thereof. The process for producing a zinc oxide-protein complex according to the present invention includes a hydrogen peroxide addition step for adding hydrogen peroxide so that the concentration would be 60 mM or greater and 150 mM or less to a buffer containing a protein having a cavity inside thereof such as ferritin, zinc ion, and ammonia.

Process for producing zinc oxide-protein complex

A novel method for two-dimensionally arraying ferritin on a substrate is provided which obviates the need for a metal ion that permits linking between adjacent two ferritin particles. In a method of two-dimensionally arraying ferritin on a substrate, the surface of the substrate is hydrophilic, and the method includes the steps of: developing a solution containing a solvent and the ferritin on the substrate; and removing the solvent from the solution developed on the substrate, while the ferritin has an amino acid sequence set out in SEQ ID NO: 1 modified at its N-terminus.

Growing community of inventors

Osaka, Japan

Kazuaki Nishio