Bio Verde Inc.

Bmg Inc.

Kazuaki Matsumura

Suong-Hyu Hyon

Hajime Sugai

Sadami Tsutsumi

A composition for cryopreservation of cells and tissues of human and other animals in a safe manner without using toxic substances such as DMSO, as well as for freeze preserving or freeze-drying of foods and pharmaceuticals. In embodiments, &#x3b5;-poly-L-lysine is reacted with succinic anhydride so that 60% or more of amino groups are blocked; and, thus obtained polymer compound is added to Dulbecco-modified eagle MEM culture medium (DMEM) on market sale to form a cryopreservation liquid. In embodiments for foods or pharmaceuticals, the &#x3b5;-poly-L-lysine derivative was added by 0.5-10 wt % to curb freeze concentration.

Composition for cryopreservation of cells and tissues

It is to provide an implant with shock-absorbing property that is able to be strongly secured in a living body as well as a manufacturing method of such implant. The implant comprising: a substrate; a first film on the substrate, which is comprised of a polymer and has a functional group that enables adsorption of calcium ions; and a second film formed on the first film and being comprised of calcium phosphate. The manufacturing method of the implant comprising: forming said first film on a substrate; and subsequently, dipping the substrate in a calcium ion solution and in a phosphate ion solution alternately as to form the second film.

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Kyoto, Japan

Kazuaki Matsumura